Pancreatic Involvement in Pediatric Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a chronic condition that includes two clinical entities: Crohn’s disease and ulcerative colitis. Although both entities mainly affect the gastrointestinal tract are considered multisystemic diseases and may present extraintestinal manifestations involving other or...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-10-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fped.2017.00218/full |
| _version_ | 1818303981718339584 |
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| author | Javier Martín-de-Carpi Melinda Moriczi Gemma Pujol-Muncunill Victor M. Navas-López Victor M. Navas-López |
| author_facet | Javier Martín-de-Carpi Melinda Moriczi Gemma Pujol-Muncunill Victor M. Navas-López Victor M. Navas-López |
| author_sort | Javier Martín-de-Carpi |
| collection | DOAJ |
| description | Inflammatory bowel disease (IBD) is a chronic condition that includes two clinical entities: Crohn’s disease and ulcerative colitis. Although both entities mainly affect the gastrointestinal tract are considered multisystemic diseases and may present extraintestinal manifestations involving other organs and systems. Pancreatic involvement in Pediatric IBD includes a heterogeneous group of clinical entities like acute pancreatitis, chronic pancreatitis, autoimmune pancreatitis, asymptomatic exocrine pancreatic insufficiency, increased pancreatic enzyme levels, structural abnormalities, and granulomatous inflammation. Although the mechanism for pancreatic involvement in IBD is not clearly elucidated, is important to keep in mind the association of these two entities in order to perform a prompt diagnosis and establish an appropriate treatment. The objective of this review is to update the available evidence on pancreatic involvement in children with IBD. |
| first_indexed | 2024-12-13T06:03:26Z |
| format | Article |
| id | doaj.art-aae7a0106df745ae91c1bdbd1a5c2054 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-12-13T06:03:26Z |
| publishDate | 2017-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-aae7a0106df745ae91c1bdbd1a5c20542022-12-21T23:57:17ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602017-10-01510.3389/fped.2017.00218283589Pancreatic Involvement in Pediatric Inflammatory Bowel DiseaseJavier Martín-de-Carpi0Melinda Moriczi1Gemma Pujol-Muncunill2Victor M. Navas-López3Victor M. Navas-López4Unit for the Comprehensive Care of Paediatric Inflammatory Bowel Disease, Hospital Sant Joan de Déu, Barcelona, SpainPediatric Gastroenterology and Nutrition Unit, Hospital Materno Infantil, Málaga, SpainUnit for the Comprehensive Care of Paediatric Inflammatory Bowel Disease, Hospital Sant Joan de Déu, Barcelona, SpainPediatric Gastroenterology and Nutrition Unit, Hospital Materno Infantil, Málaga, SpainIBIMA, Biomedical Institute of Málaga, Málaga, SpainInflammatory bowel disease (IBD) is a chronic condition that includes two clinical entities: Crohn’s disease and ulcerative colitis. Although both entities mainly affect the gastrointestinal tract are considered multisystemic diseases and may present extraintestinal manifestations involving other organs and systems. Pancreatic involvement in Pediatric IBD includes a heterogeneous group of clinical entities like acute pancreatitis, chronic pancreatitis, autoimmune pancreatitis, asymptomatic exocrine pancreatic insufficiency, increased pancreatic enzyme levels, structural abnormalities, and granulomatous inflammation. Although the mechanism for pancreatic involvement in IBD is not clearly elucidated, is important to keep in mind the association of these two entities in order to perform a prompt diagnosis and establish an appropriate treatment. The objective of this review is to update the available evidence on pancreatic involvement in children with IBD.http://journal.frontiersin.org/article/10.3389/fped.2017.00218/fullinflammatory bowel diseasepancreatitispancreatic enzymeextraintestinal manifestationschildren |
| spellingShingle | Javier Martín-de-Carpi Melinda Moriczi Gemma Pujol-Muncunill Victor M. Navas-López Victor M. Navas-López Pancreatic Involvement in Pediatric Inflammatory Bowel Disease Frontiers in Pediatrics inflammatory bowel disease pancreatitis pancreatic enzyme extraintestinal manifestations children |
| title | Pancreatic Involvement in Pediatric Inflammatory Bowel Disease |
| title_full | Pancreatic Involvement in Pediatric Inflammatory Bowel Disease |
| title_fullStr | Pancreatic Involvement in Pediatric Inflammatory Bowel Disease |
| title_full_unstemmed | Pancreatic Involvement in Pediatric Inflammatory Bowel Disease |
| title_short | Pancreatic Involvement in Pediatric Inflammatory Bowel Disease |
| title_sort | pancreatic involvement in pediatric inflammatory bowel disease |
| topic | inflammatory bowel disease pancreatitis pancreatic enzyme extraintestinal manifestations children |
| url | http://journal.frontiersin.org/article/10.3389/fped.2017.00218/full |
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