Acute leukemia in pregnancy: Case series from a tertiary care institute
Background: Acute leukemia in pregnancy is estimated to occur in less than one in one lakh pregnancies. Management of these patients differs by the trimester in which they present, because of the differential sensitivity of the fetus to chemotherapy during the three trimesters. Because of the rarity...
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| Format: | Article |
| Language: | English |
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KIMS Foundation and Research Center
2021-04-01
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| Series: | Journal of Medical and Scientific Research |
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| Online Access: | http://jmsronline.com/article.aspx?ID=Acute-leukemia-in-pregnancy-Case-series |
| _version_ | 1818789647824715776 |
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| author | Peta RK Panchal HP Patel A Parikh S Agarwal A Khanikar D Himthani N |
| author_facet | Peta RK Panchal HP Patel A Parikh S Agarwal A Khanikar D Himthani N |
| author_sort | Peta RK |
| collection | DOAJ |
| description | Background: Acute leukemia in pregnancy is estimated to occur in less than one in one lakh pregnancies. Management of these patients differs by the trimester in which they present, because of the differential sensitivity of the fetus to chemotherapy during the three trimesters. Because of the rarity of this situation, there is scarcity of data on the management of these patients.
Materials and method: We included patients with acute leukemia diagnosed and treated during pregnancy at our institute and reviewed 3 successive patients for this case series.
Results and conclusion: Acute leukemia in pregnancy presents a unique challenge for treatment and requires multidisciplinary co-ordination for treatment. When judiciously managed, good outcomes of disease of mother and fetus can be achieved. Our three patients included one in each trimester; the first trimester patient underwent medical termination of pregnancy and has successfully completed treatment. The second trimester patient underwent induction chemotherapy and delivered a healthy baby. The patient diagnosed in the third trimester delivered a pre-term healthy baby during treatment and continues to be on chemotherapy. |
| first_indexed | 2024-12-18T14:42:54Z |
| format | Article |
| id | doaj.art-aae94a05580f4839898692fccde06096 |
| institution | Directory Open Access Journal |
| issn | 2321-1326 2394-112X |
| language | English |
| last_indexed | 2024-12-18T14:42:54Z |
| publishDate | 2021-04-01 |
| publisher | KIMS Foundation and Research Center |
| record_format | Article |
| series | Journal of Medical and Scientific Research |
| spelling | doaj.art-aae94a05580f4839898692fccde060962022-12-21T21:04:21ZengKIMS Foundation and Research CenterJournal of Medical and Scientific Research2321-13262394-112X2021-04-01928590Acute leukemia in pregnancy: Case series from a tertiary care institutePeta RK0Panchal HP1Patel A2Parikh S3Agarwal A4Khanikar D5Himthani N6Department of Medical Oncology, The Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India Department of Medical Oncology, The Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India Department of Medical Oncology, The Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India Department of Medical Oncology, The Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India Department of Medical Oncology, The Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India Department of Medical Oncology, The Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India Department of Medical Oncology, The Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India Background: Acute leukemia in pregnancy is estimated to occur in less than one in one lakh pregnancies. Management of these patients differs by the trimester in which they present, because of the differential sensitivity of the fetus to chemotherapy during the three trimesters. Because of the rarity of this situation, there is scarcity of data on the management of these patients. Materials and method: We included patients with acute leukemia diagnosed and treated during pregnancy at our institute and reviewed 3 successive patients for this case series. Results and conclusion: Acute leukemia in pregnancy presents a unique challenge for treatment and requires multidisciplinary co-ordination for treatment. When judiciously managed, good outcomes of disease of mother and fetus can be achieved. Our three patients included one in each trimester; the first trimester patient underwent medical termination of pregnancy and has successfully completed treatment. The second trimester patient underwent induction chemotherapy and delivered a healthy baby. The patient diagnosed in the third trimester delivered a pre-term healthy baby during treatment and continues to be on chemotherapy.http://jmsronline.com/article.aspx?ID=Acute-leukemia-in-pregnancy-Case-seriesacute leukemia in pregnancymedical termination of pregnancychemotherapy |
| spellingShingle | Peta RK Panchal HP Patel A Parikh S Agarwal A Khanikar D Himthani N Acute leukemia in pregnancy: Case series from a tertiary care institute Journal of Medical and Scientific Research acute leukemia in pregnancy medical termination of pregnancy chemotherapy |
| title | Acute leukemia in pregnancy: Case series from a tertiary care institute |
| title_full | Acute leukemia in pregnancy: Case series from a tertiary care institute |
| title_fullStr | Acute leukemia in pregnancy: Case series from a tertiary care institute |
| title_full_unstemmed | Acute leukemia in pregnancy: Case series from a tertiary care institute |
| title_short | Acute leukemia in pregnancy: Case series from a tertiary care institute |
| title_sort | acute leukemia in pregnancy case series from a tertiary care institute |
| topic | acute leukemia in pregnancy medical termination of pregnancy chemotherapy |
| url | http://jmsronline.com/article.aspx?ID=Acute-leukemia-in-pregnancy-Case-series |
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