Steady-state estradiol triggers a unique innate immune response to allergen resulting in increased airway resistance

Highlights Steady levels of estrogen are associated with changes in allergic inflammation. When E2 is maintained at a level comparable to the mid-follicular phase of ovulation mucus production and airway hyperreactivity are increased. Estrogen reduces eosinophils and ILC2 following allergen challeng...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Kristi J. Warren, Cassandra Deering-Rice, Tom Huecksteadt, Shubhanshi Trivedi, Alessandro Venosa, Christopher Reilly, Karl Sanders, Frederic Clayton, Todd A. Wyatt, Jill A. Poole, Nicola M. Heller, Daniel Leung, Robert Paine
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: BMC 2023-01-01
Цуврал:Biology of Sex Differences
Онлайн хандалт:https://doi.org/10.1186/s13293-022-00483-7