Steady-state estradiol triggers a unique innate immune response to allergen resulting in increased airway resistance
Highlights Steady levels of estrogen are associated with changes in allergic inflammation. When E2 is maintained at a level comparable to the mid-follicular phase of ovulation mucus production and airway hyperreactivity are increased. Estrogen reduces eosinophils and ILC2 following allergen challeng...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-01-01
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| Series: | Biology of Sex Differences |
| Online Access: | https://doi.org/10.1186/s13293-022-00483-7 |