Role of high dose IV vitamin C and zinc in coronavirus
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome- related coronavirus 2 (SARS-CoV- 2), is now considered as an ongoing global pandemic. Common symptoms include pyrexia, cough, dyspnea, fatigue, sore throat, and loss of sense of taste and smell. Complications that can...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2021-02-01
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| Series: | Geriatric Care |
| Subjects: | |
| Online Access: | https://www.pagepressjournals.org/index.php/gc/article/view/9338 |
| _version_ | 1811302204975349760 |
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| author | Arooj Fatima Muhammad Usman Ali Khan Mehkaar Najeeb Muhammad Yasoob Ali Khan Faiz Ul Haq |
| author_facet | Arooj Fatima Muhammad Usman Ali Khan Mehkaar Najeeb Muhammad Yasoob Ali Khan Faiz Ul Haq |
| author_sort | Arooj Fatima |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome- related coronavirus 2 (SARS-CoV- 2), is now considered as an ongoing global pandemic. Common symptoms include pyrexia, cough, dyspnea, fatigue, sore throat, and loss of sense of taste and smell. Complications that can result from more severe insult on lung tissue is pneumonia and acute respiratory distress syndrome (ARDS), which can further lead to septic shock. It is also not uncommon to find neurological symptoms in patients suffering from COVID-19. The primary treatment for COVID-19 is symptomatic treatment and supportive care. As there is no known vaccination and antiviral therapy for this disease, there is a desperate need to find an alternative to control and stop the spread of disease. Maintaining adequate micronutrient balance might enhance the immunity and protect from viral infections as well. Vitamin C and zinc helps in improving symptoms and shortening the duration of the common cold. Vitamin C (L-ascorbic acid) possesses pleiotropic physiological activity. High dose Vitamin C has shown to be effective against the common flu, rhinovirus, avian virus, chikungunya, Zika, ARDS, and influenza, and there is evidence that supports the protective effect of high dose IV vitamin C during sepsis-induced ARDS due to COVID-19. Zinc has a profound impact on the replication of viruses. Increasing intracellular zinc concentration along with pyrithione (zinc ionophore) has been shown to impair the replication of several RNA viruses efficiently, including poliovirus, influenza virus and several picornaviruses. A combination of zinc and can also inhibit the replication of SARS-coronavirus in cell culture. |
| first_indexed | 2024-04-13T07:23:53Z |
| format | Article |
| id | doaj.art-aaeb1432e1474bc2bc6f79f5010392ed |
| institution | Directory Open Access Journal |
| issn | 2465-1109 2465-1397 |
| language | English |
| last_indexed | 2024-04-13T07:23:53Z |
| publishDate | 2021-02-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Geriatric Care |
| spelling | doaj.art-aaeb1432e1474bc2bc6f79f5010392ed2022-12-22T02:56:33ZengPAGEPress PublicationsGeriatric Care2465-11092465-13972021-02-017110.4081/gc.2021.9338Role of high dose IV vitamin C and zinc in coronavirusArooj Fatima0Muhammad Usman Ali Khan1Mehkaar Najeeb2Muhammad Yasoob Ali Khan3Faiz Ul Haq4Department of Pharmacology University of Health Sciences, LahoreDepartment of Pharmacology University of Health Sciences, LahoreDepartment of Physiology, University of Health Sciences, LahoreCombined Miltary Hospital, Multan, PakistanDepartment of Microbiology, University of Health Sciences, LahoreCoronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome- related coronavirus 2 (SARS-CoV- 2), is now considered as an ongoing global pandemic. Common symptoms include pyrexia, cough, dyspnea, fatigue, sore throat, and loss of sense of taste and smell. Complications that can result from more severe insult on lung tissue is pneumonia and acute respiratory distress syndrome (ARDS), which can further lead to septic shock. It is also not uncommon to find neurological symptoms in patients suffering from COVID-19. The primary treatment for COVID-19 is symptomatic treatment and supportive care. As there is no known vaccination and antiviral therapy for this disease, there is a desperate need to find an alternative to control and stop the spread of disease. Maintaining adequate micronutrient balance might enhance the immunity and protect from viral infections as well. Vitamin C and zinc helps in improving symptoms and shortening the duration of the common cold. Vitamin C (L-ascorbic acid) possesses pleiotropic physiological activity. High dose Vitamin C has shown to be effective against the common flu, rhinovirus, avian virus, chikungunya, Zika, ARDS, and influenza, and there is evidence that supports the protective effect of high dose IV vitamin C during sepsis-induced ARDS due to COVID-19. Zinc has a profound impact on the replication of viruses. Increasing intracellular zinc concentration along with pyrithione (zinc ionophore) has been shown to impair the replication of several RNA viruses efficiently, including poliovirus, influenza virus and several picornaviruses. A combination of zinc and can also inhibit the replication of SARS-coronavirus in cell culture.https://www.pagepressjournals.org/index.php/gc/article/view/9338COVID-19SARS-CoV-2vitamin Czinctreatment. |
| spellingShingle | Arooj Fatima Muhammad Usman Ali Khan Mehkaar Najeeb Muhammad Yasoob Ali Khan Faiz Ul Haq Role of high dose IV vitamin C and zinc in coronavirus Geriatric Care COVID-19 SARS-CoV-2 vitamin C zinc treatment. |
| title | Role of high dose IV vitamin C and zinc in coronavirus |
| title_full | Role of high dose IV vitamin C and zinc in coronavirus |
| title_fullStr | Role of high dose IV vitamin C and zinc in coronavirus |
| title_full_unstemmed | Role of high dose IV vitamin C and zinc in coronavirus |
| title_short | Role of high dose IV vitamin C and zinc in coronavirus |
| title_sort | role of high dose iv vitamin c and zinc in coronavirus |
| topic | COVID-19 SARS-CoV-2 vitamin C zinc treatment. |
| url | https://www.pagepressjournals.org/index.php/gc/article/view/9338 |
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