Single-Cell Transcriptome Analysis of Small Cell Neuroendocrine Carcinoma of the Endometrium Reveals ISL1 as a Potential Biomarker for Diagnosis and Treatment

Single-Cell Transcriptome Analysis of Small Cell Neuroendocrine Carcinoma of the Endometrium Reveals ISL1 as a Potential Biomarker for Diagnosis and Treatment

Background: As a dedifferentiated tumor, small cell endometrial neuroendocrine tumors (NETs) are rare and frequently diagnosed at an advanced stage with a poor prognosis. Current treatment recommendations are often extrapolated from histologically similar tumors in other sites or based on retrospect...

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Bibliographic Details
Main Authors: Cheng Zhong, Yu-e Guo, Qianlan Yang, Yunfeng Song, Tongshuai Wang, Bailian Cai, Hao Chen, He Du, Jing Wan, Yin Liu, Yiran Li, Xiaoping Wan
Format: Article
Language:English
Published: IMR Press 2024-03-01
Series:Frontiers in Bioscience-Landmark
Subjects:
uterine neuroendocrine tumors
single-cell rna sequencing
isl1
cell proliferation and migration
Online Access:https://www.imrpress.com/journal/FBL/29/3/10.31083/j.fbl2903100

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