Haze Exposure Changes the Skin Fungal Community and Promotes the Growth of Talaromyces Strains
ABSTRACT Haze pollution has been a public health issue. The skin microbiota, as a component of the first line of defense, is disturbed by environmental pollutants, which may have an impact on human health. A total of 74 skin samples from healthy students were collected during haze and nonhaze days i...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2023-06-01
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| Series: | Microbiology Spectrum |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/spectrum.01188-22 |
| _version_ | 1797803412107034624 |
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| author | Dong Yan Min Li Wenhao Si Shijun Ni Xin Liu Yahan Chang Xiaochan Guo Jingjing Wang Jie Bai Yuanhang Chen Haoyue Jia Tao Zhang Minna Wu Xiangfeng Song Zhongwei Tian Liyan Yu |
| author_facet | Dong Yan Min Li Wenhao Si Shijun Ni Xin Liu Yahan Chang Xiaochan Guo Jingjing Wang Jie Bai Yuanhang Chen Haoyue Jia Tao Zhang Minna Wu Xiangfeng Song Zhongwei Tian Liyan Yu |
| author_sort | Dong Yan |
| collection | DOAJ |
| description | ABSTRACT Haze pollution has been a public health issue. The skin microbiota, as a component of the first line of defense, is disturbed by environmental pollutants, which may have an impact on human health. A total of 74 skin samples from healthy students were collected during haze and nonhaze days in spring and winter. Significant differences of skin fungal community composition between haze and nonhaze days were observed in female and male samples in spring and male samples in winter based on unweighted UniFrac distance analysis. Phylogenetic diversity whole-tree indices and observed features were significantly increased during haze days in male samples in winter compared to nonhaze days, but no significant difference was observed in other groups. Dothideomycetes, Capnodiales, Mycosphaerellaceae, etc. were significantly enriched during nonhaze days, whereas Trichocomaceae, Talaromyces, and Pezizaceae were significantly enriched during haze days. Thus, five Talaromyces strains were isolated, and an in vitro culture experiment revealed that the growth of representative Talaromyces strains was increased at high concentrations of particulate matter, confirming the sequencing results. Furthermore, during haze days, the fungal community assembly was better fitted to a niche-based assembly model than during nonhaze days. Talaromyces enriched during haze days deviated from the neutral assembly process. Our findings provided a comprehensive characterization of the skin fungal community during haze and nonhaze days and elucidated novel insights into how haze exposure influences the skin fungal community. IMPORTANCE Skin fungi play an important role in human health. Particulate matter (PM), the main haze pollutant, has been a public environmental threat. However, few studies have assessed the effects of air pollutants on skin fungi. Here, haze exposure influenced the diversity and composition of the skin fungal community. In an in vitro experiment, a high concentration of PM promoted the growth of Talaromyces strains. The fungal community assembly is better fitted to a niche-based assembly model during haze days. We anticipate that this study may provide new insights on the role of haze exposure disturbing the skin fungal community. It lays the groundwork for further clarifying the association between the changes of the skin fungal community and adverse health outcomes. Our study is the first to report the changes in the skin fungal community during haze and nonhaze days, which expands the understanding of the relationship between haze and skin fungi. |
| first_indexed | 2024-03-13T05:20:22Z |
| format | Article |
| id | doaj.art-aaedba94436a4bf39ce0070d95cdb1d8 |
| institution | Directory Open Access Journal |
| issn | 2165-0497 |
| language | English |
| last_indexed | 2024-03-13T05:20:22Z |
| publishDate | 2023-06-01 |
| publisher | American Society for Microbiology |
| record_format | Article |
| series | Microbiology Spectrum |
| spelling | doaj.art-aaedba94436a4bf39ce0070d95cdb1d82023-06-15T13:18:33ZengAmerican Society for MicrobiologyMicrobiology Spectrum2165-04972023-06-0111310.1128/spectrum.01188-22Haze Exposure Changes the Skin Fungal Community and Promotes the Growth of Talaromyces StrainsDong Yan0Min Li1Wenhao Si2Shijun Ni3Xin Liu4Yahan Chang5Xiaochan Guo6Jingjing Wang7Jie Bai8Yuanhang Chen9Haoyue Jia10Tao Zhang11Minna Wu12Xiangfeng Song13Zhongwei Tian14Liyan Yu15Xinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaChina Pharmaceutical Culture Collection, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaXinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaDepartment of Immunology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, ChinaDepartment of Dermatology, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, ChinaChina Pharmaceutical Culture Collection, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaABSTRACT Haze pollution has been a public health issue. The skin microbiota, as a component of the first line of defense, is disturbed by environmental pollutants, which may have an impact on human health. A total of 74 skin samples from healthy students were collected during haze and nonhaze days in spring and winter. Significant differences of skin fungal community composition between haze and nonhaze days were observed in female and male samples in spring and male samples in winter based on unweighted UniFrac distance analysis. Phylogenetic diversity whole-tree indices and observed features were significantly increased during haze days in male samples in winter compared to nonhaze days, but no significant difference was observed in other groups. Dothideomycetes, Capnodiales, Mycosphaerellaceae, etc. were significantly enriched during nonhaze days, whereas Trichocomaceae, Talaromyces, and Pezizaceae were significantly enriched during haze days. Thus, five Talaromyces strains were isolated, and an in vitro culture experiment revealed that the growth of representative Talaromyces strains was increased at high concentrations of particulate matter, confirming the sequencing results. Furthermore, during haze days, the fungal community assembly was better fitted to a niche-based assembly model than during nonhaze days. Talaromyces enriched during haze days deviated from the neutral assembly process. Our findings provided a comprehensive characterization of the skin fungal community during haze and nonhaze days and elucidated novel insights into how haze exposure influences the skin fungal community. IMPORTANCE Skin fungi play an important role in human health. Particulate matter (PM), the main haze pollutant, has been a public environmental threat. However, few studies have assessed the effects of air pollutants on skin fungi. Here, haze exposure influenced the diversity and composition of the skin fungal community. In an in vitro experiment, a high concentration of PM promoted the growth of Talaromyces strains. The fungal community assembly is better fitted to a niche-based assembly model during haze days. We anticipate that this study may provide new insights on the role of haze exposure disturbing the skin fungal community. It lays the groundwork for further clarifying the association between the changes of the skin fungal community and adverse health outcomes. Our study is the first to report the changes in the skin fungal community during haze and nonhaze days, which expands the understanding of the relationship between haze and skin fungi.https://journals.asm.org/doi/10.1128/spectrum.01188-22skin fungihazeparticulate mattercommunity compositiondiversity |
| spellingShingle | Dong Yan Min Li Wenhao Si Shijun Ni Xin Liu Yahan Chang Xiaochan Guo Jingjing Wang Jie Bai Yuanhang Chen Haoyue Jia Tao Zhang Minna Wu Xiangfeng Song Zhongwei Tian Liyan Yu Haze Exposure Changes the Skin Fungal Community and Promotes the Growth of Talaromyces Strains Microbiology Spectrum skin fungi haze particulate matter community composition diversity |
| title | Haze Exposure Changes the Skin Fungal Community and Promotes the Growth of Talaromyces Strains |
| title_full | Haze Exposure Changes the Skin Fungal Community and Promotes the Growth of Talaromyces Strains |
| title_fullStr | Haze Exposure Changes the Skin Fungal Community and Promotes the Growth of Talaromyces Strains |
| title_full_unstemmed | Haze Exposure Changes the Skin Fungal Community and Promotes the Growth of Talaromyces Strains |
| title_short | Haze Exposure Changes the Skin Fungal Community and Promotes the Growth of Talaromyces Strains |
| title_sort | haze exposure changes the skin fungal community and promotes the growth of talaromyces strains |
| topic | skin fungi haze particulate matter community composition diversity |
| url | https://journals.asm.org/doi/10.1128/spectrum.01188-22 |
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