Physical Health in Clinical High Risk for Psychosis Individuals: A Cross-Sectional Study
Background: The clinical high risk for psychosis (CHR-P) phase represents an opportunity for prevention and early intervention in young adults, which also could focus on improving physical health trajectories. Methods: We conducted a RECORD-compliant clinical register-based cohort study. The primary...
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MDPI AG
2023-01-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/13/1/128 |
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| author | Umberto Provenzani Andrea De Micheli Stefano Damiani Dominic Oliver Natascia Brondino Paolo Fusar-Poli |
| author_facet | Umberto Provenzani Andrea De Micheli Stefano Damiani Dominic Oliver Natascia Brondino Paolo Fusar-Poli |
| author_sort | Umberto Provenzani |
| collection | DOAJ |
| description | Background: The clinical high risk for psychosis (CHR-P) phase represents an opportunity for prevention and early intervention in young adults, which also could focus on improving physical health trajectories. Methods: We conducted a RECORD-compliant clinical register-based cohort study. The primary outcome was to describe the physical health of assessed CHR-P individuals, obtained via Electronic Health Records at the South London and Maudsley (SLaM) NHS Foundation Trust, UK (January 2013–October 2020). Results: The final database included 194 CHR-P subjects (46% female). Mean age was 23.70 ± 5.12 years. Percentage of tobacco smokers was 41% (significantly higher than in the age-matched general population [24%]). We found that 49% of subjects who consumed alcohol had an AUDIT-C (Alcohol Use Disorder Identification Test) score above 5 (hazardous drinking), with an average score of 4.94 (significantly higher than in the general population [2.75]). Investigating diet revealed low fiber intake in most subjects and high saturated fat intake in 10% of the individuals. We found that 47% of CHR-P subjects met the UK recommended physical activity guidelines (significantly lower than in the general population [66%]). Physical parameters (e.g., weight, heart rate, blood pressure) were not significantly different from the general population. Conclusions: This evidence corroborates the need for monitoring physical health parameters in CHR-P subjects, to implement tailored interventions that target daily habits. |
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| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-09T13:22:38Z |
| publishDate | 2023-01-01 |
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| series | Brain Sciences |
| spelling | doaj.art-aaf0ac6001de4c5f993e478ed16e7a072023-11-30T21:28:02ZengMDPI AGBrain Sciences2076-34252023-01-0113112810.3390/brainsci13010128Physical Health in Clinical High Risk for Psychosis Individuals: A Cross-Sectional StudyUmberto Provenzani0Andrea De Micheli1Stefano Damiani2Dominic Oliver3Natascia Brondino4Paolo Fusar-Poli5Department of Brain and Behavioural Sciences, University of Pavia, 27100 Pavia, ItalyEarly Psychosis, Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London SE5 8AF, UKDepartment of Brain and Behavioural Sciences, University of Pavia, 27100 Pavia, ItalyEarly Psychosis, Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London SE5 8AF, UKDepartment of Brain and Behavioural Sciences, University of Pavia, 27100 Pavia, ItalyDepartment of Brain and Behavioural Sciences, University of Pavia, 27100 Pavia, ItalyBackground: The clinical high risk for psychosis (CHR-P) phase represents an opportunity for prevention and early intervention in young adults, which also could focus on improving physical health trajectories. Methods: We conducted a RECORD-compliant clinical register-based cohort study. The primary outcome was to describe the physical health of assessed CHR-P individuals, obtained via Electronic Health Records at the South London and Maudsley (SLaM) NHS Foundation Trust, UK (January 2013–October 2020). Results: The final database included 194 CHR-P subjects (46% female). Mean age was 23.70 ± 5.12 years. Percentage of tobacco smokers was 41% (significantly higher than in the age-matched general population [24%]). We found that 49% of subjects who consumed alcohol had an AUDIT-C (Alcohol Use Disorder Identification Test) score above 5 (hazardous drinking), with an average score of 4.94 (significantly higher than in the general population [2.75]). Investigating diet revealed low fiber intake in most subjects and high saturated fat intake in 10% of the individuals. We found that 47% of CHR-P subjects met the UK recommended physical activity guidelines (significantly lower than in the general population [66%]). Physical parameters (e.g., weight, heart rate, blood pressure) were not significantly different from the general population. Conclusions: This evidence corroborates the need for monitoring physical health parameters in CHR-P subjects, to implement tailored interventions that target daily habits.https://www.mdpi.com/2076-3425/13/1/128physical healthpsychosisriskCHR-P |
| spellingShingle | Umberto Provenzani Andrea De Micheli Stefano Damiani Dominic Oliver Natascia Brondino Paolo Fusar-Poli Physical Health in Clinical High Risk for Psychosis Individuals: A Cross-Sectional Study Brain Sciences physical health psychosis risk CHR-P |
| title | Physical Health in Clinical High Risk for Psychosis Individuals: A Cross-Sectional Study |
| title_full | Physical Health in Clinical High Risk for Psychosis Individuals: A Cross-Sectional Study |
| title_fullStr | Physical Health in Clinical High Risk for Psychosis Individuals: A Cross-Sectional Study |
| title_full_unstemmed | Physical Health in Clinical High Risk for Psychosis Individuals: A Cross-Sectional Study |
| title_short | Physical Health in Clinical High Risk for Psychosis Individuals: A Cross-Sectional Study |
| title_sort | physical health in clinical high risk for psychosis individuals a cross sectional study |
| topic | physical health psychosis risk CHR-P |
| url | https://www.mdpi.com/2076-3425/13/1/128 |
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