Evaluation of ATM Kinase Inhibitor KU-55933 as Potential Anti-Toxoplasma gondii Agent

Evaluation of ATM Kinase Inhibitor KU-55933 as Potential Anti-Toxoplasma gondii Agent

Toxoplasma gondii is an apicomplexan protozoan parasite with a complex life cycle composed of multiple stages that infect mammals and birds. Tachyzoites rapidly replicate within host cells to produce acute infection during which the parasite disseminates to tissues and organs. Highly replicative cel...

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Bibliographic Details
Main Authors: Jonathan Munera López, Agustina Ganuza, Silvina S. Bogado, Daniela Muñoz, Diego M. Ruiz, William J. Sullivan, Laura Vanagas, Sergio O. Angel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Toxoplasma gondii
DNA repair
cell cycle
fork collapse
antiparasitic drugs
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00026/full

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