Mycn regulates intestinal development through ribosomal biogenesis in a zebrafish model of Feingold syndrome 1

Feingold syndrome type 1, caused by loss-of-function of MYCN, is characterized by varied phenotypes including esophageal and duodenal atresia. However, no adequate model exists for studying the syndrome’s pathological or molecular mechanisms, nor is there a treatment strategy. Here, we developed a z...

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Bibliographic Details
Main Authors: Yun-Fei Li, Tao Cheng, Ying-Jie Zhang, Xin-Xin Fu, Jing Mo, Guo-Qin Zhao, Mao-Guang Xue, Ding-Hao Zhuo, Yan-Yi Xing, Ying Huang, Xiao-Zhi Sun, Dan Wang, Xiang Liu, Yang Dong, Xiao-Sheng Zhu, Feng He, Jun Ma, Dong Chen, Xi Jin, Peng-Fei Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-11-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624419/?tool=EBI