Association of Grip Strength with obesity & cortisol; Possible indicators of biological ageing

Background: Cortisol has a positive correlation with Obesity, which indicates a relation between obesity and cortisol. Furthermore, there are increased chances of demolished muscle strength up to two times with elevated levels of cortisol. Thus, the aim of the study was to assess the impact of incre...

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Main Authors: Faizan Mirza, Amaila Fazal, Khadija Shabbir, Hafsa Farooq, Sadaf Ahmed
Format: Article
Language:English
Published: Advance Educational Institute & Research Centre 2020-09-01
Series:International Journal of Endorsing Health Science Research
Subjects:
Online Access:http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/266/596
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author Faizan Mirza
Amaila Fazal
Khadija Shabbir
Hafsa Farooq
Sadaf Ahmed
author_facet Faizan Mirza
Amaila Fazal
Khadija Shabbir
Hafsa Farooq
Sadaf Ahmed
author_sort Faizan Mirza
collection DOAJ
description Background: Cortisol has a positive correlation with Obesity, which indicates a relation between obesity and cortisol. Furthermore, there are increased chances of demolished muscle strength up to two times with elevated levels of cortisol. Thus, the aim of the study was to assess the impact of increased cortisol levels on the grip strength and to determine that the grip strength is a possible indicator for accelerated biological ageing. Methodology: This cross-sectional, purposive sampling study was conducted in Karachi, Pakistan. Overall 412 were recruited to participate in the study, the data for age, gender, BMI, grip strength, and cortisol was collected from the participants. The age-wise correlates of hand grip strength were assessed using Multiple linear regression analysis and the mean decline in the grip strength with advancing age is displayed. Results: The mean Grip strength of the overall population was 30.75±14.35. It was observed that there was a negative significant correlation between the age and the grip strength (F = 3.57; r= -0.27; p=0.007) i.e. with increasing age a gradual decrease in the grip strength was observed. BMI (Obesity) was also significantly associated with grip strength (p=0.000). Moreover, females were more likely to have weak muscle strength as compared to males (p=0.000). However, no significant association was observed among the grip strength, socioeconomic status & longevity in any of the studied age groups (p>0.05). While a significant correlation was found between Grip strength and Obesity as well as between Obesity and Cortisol. Conclusion: Thus it can be concluded that obese individuals had increased chances of accelerated biological ageing due to an increase in cortisol, and a weakened grip strength is an indicator of it.
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spelling doaj.art-aaff921598e9411aa8f91c6da26f5ee52022-12-21T17:22:58ZengAdvance Educational Institute & Research CentreInternational Journal of Endorsing Health Science Research2307-37482310-38412020-09-0183145152https://doi.org/10.29052/IJEHSR.v8.i3.2020.145-152Association of Grip Strength with obesity & cortisol; Possible indicators of biological ageingFaizan Mirza0Amaila Fazal1Khadija Shabbir2Hafsa Farooq3Sadaf Ahmed41. Department of Physiology, University of Karachi 2. Psychophysiology Research Lab, MAHQ Biological Research Centre, University of Karachi1. Department of Physiology, University of Karachi1. Department of Physiology, University of Karachi 2. Psychophysiology Research Lab, MAHQ Biological Research Centre, University of Karachi1. Department of Physiology, University of Karachi 2. Psychophysiology Research Lab, MAHQ Biological Research Centre, University of Karachi1. Psychophysiology Research Lab, University of Karachi 2. Advance Educational Institute & Research CentreBackground: Cortisol has a positive correlation with Obesity, which indicates a relation between obesity and cortisol. Furthermore, there are increased chances of demolished muscle strength up to two times with elevated levels of cortisol. Thus, the aim of the study was to assess the impact of increased cortisol levels on the grip strength and to determine that the grip strength is a possible indicator for accelerated biological ageing. Methodology: This cross-sectional, purposive sampling study was conducted in Karachi, Pakistan. Overall 412 were recruited to participate in the study, the data for age, gender, BMI, grip strength, and cortisol was collected from the participants. The age-wise correlates of hand grip strength were assessed using Multiple linear regression analysis and the mean decline in the grip strength with advancing age is displayed. Results: The mean Grip strength of the overall population was 30.75±14.35. It was observed that there was a negative significant correlation between the age and the grip strength (F = 3.57; r= -0.27; p=0.007) i.e. with increasing age a gradual decrease in the grip strength was observed. BMI (Obesity) was also significantly associated with grip strength (p=0.000). Moreover, females were more likely to have weak muscle strength as compared to males (p=0.000). However, no significant association was observed among the grip strength, socioeconomic status & longevity in any of the studied age groups (p>0.05). While a significant correlation was found between Grip strength and Obesity as well as between Obesity and Cortisol. Conclusion: Thus it can be concluded that obese individuals had increased chances of accelerated biological ageing due to an increase in cortisol, and a weakened grip strength is an indicator of it.http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/266/596ageinggrip strengthcortisolobesitysocioeconomic statuslongevity.
spellingShingle Faizan Mirza
Amaila Fazal
Khadija Shabbir
Hafsa Farooq
Sadaf Ahmed
Association of Grip Strength with obesity & cortisol; Possible indicators of biological ageing
International Journal of Endorsing Health Science Research
ageing
grip strength
cortisol
obesity
socioeconomic status
longevity.
title Association of Grip Strength with obesity & cortisol; Possible indicators of biological ageing
title_full Association of Grip Strength with obesity & cortisol; Possible indicators of biological ageing
title_fullStr Association of Grip Strength with obesity & cortisol; Possible indicators of biological ageing
title_full_unstemmed Association of Grip Strength with obesity & cortisol; Possible indicators of biological ageing
title_short Association of Grip Strength with obesity & cortisol; Possible indicators of biological ageing
title_sort association of grip strength with obesity cortisol possible indicators of biological ageing
topic ageing
grip strength
cortisol
obesity
socioeconomic status
longevity.
url http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/266/596
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AT hafsafarooq associationofgripstrengthwithobesitycortisolpossibleindicatorsofbiologicalageing
AT sadafahmed associationofgripstrengthwithobesitycortisolpossibleindicatorsofbiologicalageing