Optimization of the Process for Preparing Effervescent Tablets from Aqueous Extraction of Ficus hirta Vahl
To study the preparation process of Ficus hirta Vahl effervescent tablets, the active ingredients were extracted with the aid of ultrasound using water as solvent, and the extract species were determined by high performance liquid chromatography-mass spectrometry (HPLC-MS/MS), and the formulation of...
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The editorial department of Science and Technology of Food Industry
2024-04-01
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| Series: | Shipin gongye ke-ji |
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| Online Access: | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023050326 |
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| author | Lin YANG Rongqian JIANG Hangying ZHANG Shuyu LI Malu WU Juncheng ZHANG |
| author_facet | Lin YANG Rongqian JIANG Hangying ZHANG Shuyu LI Malu WU Juncheng ZHANG |
| author_sort | Lin YANG |
| collection | DOAJ |
| description | To study the preparation process of Ficus hirta Vahl effervescent tablets, the active ingredients were extracted with the aid of ultrasound using water as solvent, and the extract species were determined by high performance liquid chromatography-mass spectrometry (HPLC-MS/MS), and the formulation of Ficus hirta Vahl effervescent tablets was optimized by single-factor experiments and orthogonal optimization experiment. The results showed that 433 substances were detected in the aqueous extract of Ficus hirta Vahl, and the three most species were carboxylic acids and derivatives (103 species), fatty acyls (45 species) and benzene and substituted derivatives (36 species). The main active ingredients were 23 sugars (6.71% content), 9 flavonoids (0.22% content), 16 phenols (1.65% content), 5 coumarins (0.51‰ content) and 9 phenylpropanoic acids. The best preparation conditions of the effervescent tablets were 25% dried aqueous extract of Ficus hirta Vahl, 50% disintegrant (1:1.5 mass ratio of citric acid to sodium bicarbonate), 20% mannitol, 5% PEG-6000, and the solution of Ficus hirta Vahl effervescent tablets was brownish-yellow, clear and transparent with a sweet and sour taste. The DPPH free radical scavenging ability IC50 was 1.65 mg/mL. The preparation of effervescent tablets from the aqueous extract of Ficus hirta Vahl was rich in active ingredients and possesses antioxidant activity. |
| first_indexed | 2024-04-24T05:56:57Z |
| format | Article |
| id | doaj.art-ab03deffafb443c4b378eb4e5495042b |
| institution | Directory Open Access Journal |
| issn | 1002-0306 |
| language | zho |
| last_indexed | 2024-04-24T05:56:57Z |
| publishDate | 2024-04-01 |
| publisher | The editorial department of Science and Technology of Food Industry |
| record_format | Article |
| series | Shipin gongye ke-ji |
| spelling | doaj.art-ab03deffafb443c4b378eb4e5495042b2024-04-23T08:59:17ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062024-04-0145820020710.13386/j.issn1002-0306.20230503262023050326-8Optimization of the Process for Preparing Effervescent Tablets from Aqueous Extraction of Ficus hirta VahlLin YANG0Rongqian JIANG1Hangying ZHANG2Shuyu LI3Malu WU4Juncheng ZHANG5Fujian Provincial Medical Plant Exploitation and Utilization Engineering Research Center, School of Resources and Chemical Engineering, Sanming University, Sanming 365000, ChinaFujian Provincial Medical Plant Exploitation and Utilization Engineering Research Center, School of Resources and Chemical Engineering, Sanming University, Sanming 365000, ChinaFujian Provincial Medical Plant Exploitation and Utilization Engineering Research Center, School of Resources and Chemical Engineering, Sanming University, Sanming 365000, ChinaFujian Provincial Medical Plant Exploitation and Utilization Engineering Research Center, School of Resources and Chemical Engineering, Sanming University, Sanming 365000, ChinaFujian Provincial Medical Plant Exploitation and Utilization Engineering Research Center, School of Resources and Chemical Engineering, Sanming University, Sanming 365000, ChinaFujian Provincial Medical Plant Exploitation and Utilization Engineering Research Center, School of Resources and Chemical Engineering, Sanming University, Sanming 365000, ChinaTo study the preparation process of Ficus hirta Vahl effervescent tablets, the active ingredients were extracted with the aid of ultrasound using water as solvent, and the extract species were determined by high performance liquid chromatography-mass spectrometry (HPLC-MS/MS), and the formulation of Ficus hirta Vahl effervescent tablets was optimized by single-factor experiments and orthogonal optimization experiment. The results showed that 433 substances were detected in the aqueous extract of Ficus hirta Vahl, and the three most species were carboxylic acids and derivatives (103 species), fatty acyls (45 species) and benzene and substituted derivatives (36 species). The main active ingredients were 23 sugars (6.71% content), 9 flavonoids (0.22% content), 16 phenols (1.65% content), 5 coumarins (0.51‰ content) and 9 phenylpropanoic acids. The best preparation conditions of the effervescent tablets were 25% dried aqueous extract of Ficus hirta Vahl, 50% disintegrant (1:1.5 mass ratio of citric acid to sodium bicarbonate), 20% mannitol, 5% PEG-6000, and the solution of Ficus hirta Vahl effervescent tablets was brownish-yellow, clear and transparent with a sweet and sour taste. The DPPH free radical scavenging ability IC50 was 1.65 mg/mL. The preparation of effervescent tablets from the aqueous extract of Ficus hirta Vahl was rich in active ingredients and possesses antioxidant activity.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023050326ficus hirta vahlaqueous extractionactive ingredientseffervescent tabletpreparation process |
| spellingShingle | Lin YANG Rongqian JIANG Hangying ZHANG Shuyu LI Malu WU Juncheng ZHANG Optimization of the Process for Preparing Effervescent Tablets from Aqueous Extraction of Ficus hirta Vahl Shipin gongye ke-ji ficus hirta vahl aqueous extraction active ingredients effervescent tablet preparation process |
| title | Optimization of the Process for Preparing Effervescent Tablets from Aqueous Extraction of Ficus hirta Vahl |
| title_full | Optimization of the Process for Preparing Effervescent Tablets from Aqueous Extraction of Ficus hirta Vahl |
| title_fullStr | Optimization of the Process for Preparing Effervescent Tablets from Aqueous Extraction of Ficus hirta Vahl |
| title_full_unstemmed | Optimization of the Process for Preparing Effervescent Tablets from Aqueous Extraction of Ficus hirta Vahl |
| title_short | Optimization of the Process for Preparing Effervescent Tablets from Aqueous Extraction of Ficus hirta Vahl |
| title_sort | optimization of the process for preparing effervescent tablets from aqueous extraction of ficus hirta vahl |
| topic | ficus hirta vahl aqueous extraction active ingredients effervescent tablet preparation process |
| url | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023050326 |
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