Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report
Hump-nosed viper bites are frequent in southern India and Sri Lanka. However, the published literature on this snakebite is limited and its venom composition is not well characterized. In this case, we report a patient with thrombotic thrombocytopenic purpura-like syndrome following envenoming which...
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| Format: | Article |
| Language: | English |
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SciELO
2014-08-01
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| Series: | Journal of Venomous Animals and Toxins including Tropical Diseases |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200504&lng=en&tlng=en |
| _version_ | 1818790625942700032 |
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| author | Milinda Withana Chaturaka Rodrigo Ariaranee Gnanathasan Lallindra Gooneratne |
| author_facet | Milinda Withana Chaturaka Rodrigo Ariaranee Gnanathasan Lallindra Gooneratne |
| author_sort | Milinda Withana |
| collection | DOAJ |
| description | Hump-nosed viper bites are frequent in southern India and Sri Lanka. However, the published literature on this snakebite is limited and its venom composition is not well characterized. In this case, we report a patient with thrombotic thrombocytopenic purpura-like syndrome following envenoming which, to the best of our knowledge, has not been reported in the literature before. A 55-year-old woman from southern Sri Lanka presented to the local hospital 12 hours after a hump-nosed viper (Hypnale hypnale) bite. Five days later, she developed a syndrome that was characteristic of thrombotic thrombocytopenic purpura with fever, thrombocytopenia, microangiopathic hemolysis, renal impairment and neurological dysfunction in the form of confusion and coma. Her clinical syndrome and relevant laboratory parameters improved after she was treated with therapeutic plasma exchange. We compared our observations on this patient with the current literature and concluded that thrombotic thrombocytopenic purpura is a theoretically plausible yet unreported manifestation of hump-nosed viper bite up to this moment. This study also provides an important message for clinicians to look out for this complication in hump-nosed viper bites since timely treatment can be lifesaving. |
| first_indexed | 2024-12-18T14:58:26Z |
| format | Article |
| id | doaj.art-ab0518634b42430eb62b24fa883d6852 |
| institution | Directory Open Access Journal |
| issn | 1678-9199 |
| language | English |
| last_indexed | 2024-12-18T14:58:26Z |
| publishDate | 2014-08-01 |
| publisher | SciELO |
| record_format | Article |
| series | Journal of Venomous Animals and Toxins including Tropical Diseases |
| spelling | doaj.art-ab0518634b42430eb62b24fa883d68522022-12-21T21:04:00ZengSciELOJournal of Venomous Animals and Toxins including Tropical Diseases1678-91992014-08-0120010.1186/1678-9199-20-26S1678-91992014000200504Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case reportMilinda WithanaChaturaka RodrigoAriaranee GnanathasanLallindra GooneratneHump-nosed viper bites are frequent in southern India and Sri Lanka. However, the published literature on this snakebite is limited and its venom composition is not well characterized. In this case, we report a patient with thrombotic thrombocytopenic purpura-like syndrome following envenoming which, to the best of our knowledge, has not been reported in the literature before. A 55-year-old woman from southern Sri Lanka presented to the local hospital 12 hours after a hump-nosed viper (Hypnale hypnale) bite. Five days later, she developed a syndrome that was characteristic of thrombotic thrombocytopenic purpura with fever, thrombocytopenia, microangiopathic hemolysis, renal impairment and neurological dysfunction in the form of confusion and coma. Her clinical syndrome and relevant laboratory parameters improved after she was treated with therapeutic plasma exchange. We compared our observations on this patient with the current literature and concluded that thrombotic thrombocytopenic purpura is a theoretically plausible yet unreported manifestation of hump-nosed viper bite up to this moment. This study also provides an important message for clinicians to look out for this complication in hump-nosed viper bites since timely treatment can be lifesaving.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200504&lng=en&tlng=enThrombotic thrombocytopenic purpuraHump-nosed viperThrombotic microangiopathySnakebiteHemolytic uremic syndrome |
| spellingShingle | Milinda Withana Chaturaka Rodrigo Ariaranee Gnanathasan Lallindra Gooneratne Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report Journal of Venomous Animals and Toxins including Tropical Diseases Thrombotic thrombocytopenic purpura Hump-nosed viper Thrombotic microangiopathy Snakebite Hemolytic uremic syndrome |
| title | Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
| title_full | Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
| title_fullStr | Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
| title_full_unstemmed | Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
| title_short | Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
| title_sort | presumptive thrombotic thrombocytopenic purpura following a hump nosed viper hypnale hypnale bite a case report |
| topic | Thrombotic thrombocytopenic purpura Hump-nosed viper Thrombotic microangiopathy Snakebite Hemolytic uremic syndrome |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200504&lng=en&tlng=en |
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