Response to Imported Case of Marburg Hemorrhagic Fever, the Netherlands

On July 10, 2008, Marburg hemorrhagic fever was confirmed in a Dutch patient who had vacationed recently in Uganda. Exposure most likely occurred in the Python Cave (Maramagambo Forest), which harbors bat species that elsewhere in Africa have been found positive for Marburg virus. A multidisciplinar...

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Main Authors: Aura Timen, Marion P.G. Koopmans, Ann C.T.M. Vossen, Gerard J.J. van Doornum, Stephan Günther, Franchette van den Berkmortel, Kees M. Verduin, Sabine Dittrich, Petra Emmerich, Albert D.M.E. Osterhaus, Jaap T. van Dissel, Roel A. Coutinho
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2009-08-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/15/8/09-0015_article
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author Aura Timen
Marion P.G. Koopmans
Ann C.T.M. Vossen
Gerard J.J. van Doornum
Stephan Günther
Franchette van den Berkmortel
Kees M. Verduin
Sabine Dittrich
Petra Emmerich
Albert D.M.E. Osterhaus
Jaap T. van Dissel
Roel A. Coutinho
author_facet Aura Timen
Marion P.G. Koopmans
Ann C.T.M. Vossen
Gerard J.J. van Doornum
Stephan Günther
Franchette van den Berkmortel
Kees M. Verduin
Sabine Dittrich
Petra Emmerich
Albert D.M.E. Osterhaus
Jaap T. van Dissel
Roel A. Coutinho
author_sort Aura Timen
collection DOAJ
description On July 10, 2008, Marburg hemorrhagic fever was confirmed in a Dutch patient who had vacationed recently in Uganda. Exposure most likely occurred in the Python Cave (Maramagambo Forest), which harbors bat species that elsewhere in Africa have been found positive for Marburg virus. A multidisciplinary response team was convened to perform a structured risk assessment, perform risk classification of contacts, issue guidelines for follow-up, provide information, and monitor the crisis response. In total, 130 contacts were identified (66 classified as high risk and 64 as low risk) and monitored for 21 days after their last possible exposure. The case raised questions specific to international travel, postexposure prophylaxis for Marburg virus, and laboratory testing of contacts with fever. We present lessons learned and results of the follow-up serosurvey of contacts and focus on factors that prevented overreaction during an event with a high public health impact.
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spelling doaj.art-ab06f63b16784ca394a2ef4acc36c0dc2022-12-22T03:16:26ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592009-08-011581171117510.3201/eid1508.090015Response to Imported Case of Marburg Hemorrhagic Fever, the NetherlandsAura TimenMarion P.G. KoopmansAnn C.T.M. VossenGerard J.J. van DoornumStephan GüntherFranchette van den BerkmortelKees M. VerduinSabine DittrichPetra EmmerichAlbert D.M.E. OsterhausJaap T. van DisselRoel A. CoutinhoOn July 10, 2008, Marburg hemorrhagic fever was confirmed in a Dutch patient who had vacationed recently in Uganda. Exposure most likely occurred in the Python Cave (Maramagambo Forest), which harbors bat species that elsewhere in Africa have been found positive for Marburg virus. A multidisciplinary response team was convened to perform a structured risk assessment, perform risk classification of contacts, issue guidelines for follow-up, provide information, and monitor the crisis response. In total, 130 contacts were identified (66 classified as high risk and 64 as low risk) and monitored for 21 days after their last possible exposure. The case raised questions specific to international travel, postexposure prophylaxis for Marburg virus, and laboratory testing of contacts with fever. We present lessons learned and results of the follow-up serosurvey of contacts and focus on factors that prevented overreaction during an event with a high public health impact.https://wwwnc.cdc.gov/eid/article/15/8/09-0015_articleMarburg virus diseaseshemorrhagic feverexposurecontactstemperature monitoringfilovirus
spellingShingle Aura Timen
Marion P.G. Koopmans
Ann C.T.M. Vossen
Gerard J.J. van Doornum
Stephan Günther
Franchette van den Berkmortel
Kees M. Verduin
Sabine Dittrich
Petra Emmerich
Albert D.M.E. Osterhaus
Jaap T. van Dissel
Roel A. Coutinho
Response to Imported Case of Marburg Hemorrhagic Fever, the Netherlands
Emerging Infectious Diseases
Marburg virus diseases
hemorrhagic fever
exposure
contacts
temperature monitoring
filovirus
title Response to Imported Case of Marburg Hemorrhagic Fever, the Netherlands
title_full Response to Imported Case of Marburg Hemorrhagic Fever, the Netherlands
title_fullStr Response to Imported Case of Marburg Hemorrhagic Fever, the Netherlands
title_full_unstemmed Response to Imported Case of Marburg Hemorrhagic Fever, the Netherlands
title_short Response to Imported Case of Marburg Hemorrhagic Fever, the Netherlands
title_sort response to imported case of marburg hemorrhagic fever the netherlands
topic Marburg virus diseases
hemorrhagic fever
exposure
contacts
temperature monitoring
filovirus
url https://wwwnc.cdc.gov/eid/article/15/8/09-0015_article
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