Sirtuin 7 Inhibitor Attenuates Colonic Mucosal Immune Activation in Mice—Potential Therapeutic Target in Inflammatory Bowel Disease

Sirtuin 7 Inhibitor Attenuates Colonic Mucosal Immune Activation in Mice—Potential Therapeutic Target in Inflammatory Bowel Disease

Accumulating evidence has shown that sirtuin 7 (SIRT7), a mediator of various cellular activities, plays an important role in the pathogenesis of various immune-mediated inflammatory disorders. However, information remains limited regarding the role of SIRT7 in intestinal inflammation. We used a mur...

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Bibliographic Details
Main Authors: Sanghyun Kim, Junhyoung Byun, Semyung Jung, Byoungjae Kim, Kangwon Lee, Hanjo Jeon, Jaemin Lee, Hyuksoon Choi, Eunsun Kim, Yoontae Jeen, Hongsik Lee, Hoonjai Chun, Bora Keum, Taehoon Kim
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomedicines
Subjects:
sirtuin
inflammatory bowel disease
SIRT7
Online Access:https://www.mdpi.com/2227-9059/10/11/2693

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