The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat
Background: Taraxacum Officinale is a medical plant with antioxidant benefit effects. The aim of the present study is to evaluate the effect of Taraxacum Officinale alcoholic extract on serum thyroid hormone levels in adult male rat. Material and Methods: In this experimental study,45 adult male wis...
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Alborz University of Medical Sciencs
2018-08-01
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| Series: | Bihdād |
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| Online Access: | http://aums.abzums.ac.ir/browse.php?a_code=A-10-1-216&slc_lang=en&sid=1 |
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| author | Razieh Dehghanian Seyyed Ebrahim Hosseini Esfandiar Sharifi Davood Moghadamnia |
| author_facet | Razieh Dehghanian Seyyed Ebrahim Hosseini Esfandiar Sharifi Davood Moghadamnia |
| author_sort | Razieh Dehghanian |
| collection | DOAJ |
| description | Background: Taraxacum Officinale is a medical plant with antioxidant benefit effects. The aim of the present study is to evaluate the effect of Taraxacum Officinale alcoholic extract on serum thyroid hormone levels in adult male rat.
Material and Methods: In this experimental study,45 adult male wistar rats were approximate average weight body of 200-250 gr were divided in to 5 groups of 9. Control ,sham ,and three experimental groups which received 50,100,150mg/kg of Taraxacum Officinale alcoholic extract by used gavage method. After this period (14 days) blood sample were collected and after measuring the amount of thyroid hormones of T3,T4,TSH hormones, data were analyzed by using SPSS software , ANOVA and t-test.
Results: The results showed that body weight average and serum level of T4 hormone in receiving maximum dose of Taraxacum Officinale alcoholic extract showed significant decrease comparing to control group. T3 serum level in experimental groups receiving Taraxacum Officinale alcoholic extract didn't show any significant difference comparing to control group. TSH serum level in experimental groups receiving Taraxacum Officinale alcoholic extract showed significant decrease comparing to control group (p<0.05).
Conclusion: The Taraxacum Officinale alcoholic extract reduced serum thyroid hormone levels in adult male rat. |
| first_indexed | 2024-12-14T18:40:04Z |
| format | Article |
| id | doaj.art-ab096875515b4c649c80bf8814da3e7c |
| institution | Directory Open Access Journal |
| issn | 1735-6679 |
| language | fas |
| last_indexed | 2024-12-14T18:40:04Z |
| publishDate | 2018-08-01 |
| publisher | Alborz University of Medical Sciencs |
| record_format | Article |
| series | Bihdād |
| spelling | doaj.art-ab096875515b4c649c80bf8814da3e7c2022-12-21T22:51:31ZfasAlborz University of Medical SciencsBihdād1735-66792018-08-0173213219The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male RatRazieh Dehghanian0Seyyed Ebrahim Hosseini1Esfandiar Sharifi2Davood Moghadamnia3 M.Sc in Animal Physiology, Department of Biology, Kazerun Branch, Islamic Azad University, Kazerun, Iran Associated Professor in Animal Physiology, Department of Biology, Shiraz Branch, Islamic Azad University, Shiraz, Iran Instructor, Department of Biology, Kazerun Branch, Islamic Azad University, Kazerun, Iran Ph.D in Animal Physiology, Young Researchers and Elite Club, Shiraz Branch, Islamic Azad University, Shiraz, Iran Background: Taraxacum Officinale is a medical plant with antioxidant benefit effects. The aim of the present study is to evaluate the effect of Taraxacum Officinale alcoholic extract on serum thyroid hormone levels in adult male rat. Material and Methods: In this experimental study,45 adult male wistar rats were approximate average weight body of 200-250 gr were divided in to 5 groups of 9. Control ,sham ,and three experimental groups which received 50,100,150mg/kg of Taraxacum Officinale alcoholic extract by used gavage method. After this period (14 days) blood sample were collected and after measuring the amount of thyroid hormones of T3,T4,TSH hormones, data were analyzed by using SPSS software , ANOVA and t-test. Results: The results showed that body weight average and serum level of T4 hormone in receiving maximum dose of Taraxacum Officinale alcoholic extract showed significant decrease comparing to control group. T3 serum level in experimental groups receiving Taraxacum Officinale alcoholic extract didn't show any significant difference comparing to control group. TSH serum level in experimental groups receiving Taraxacum Officinale alcoholic extract showed significant decrease comparing to control group (p<0.05). Conclusion: The Taraxacum Officinale alcoholic extract reduced serum thyroid hormone levels in adult male rat.http://aums.abzums.ac.ir/browse.php?a_code=A-10-1-216&slc_lang=en&sid=1Taraxacum OfficinaleT3 T4TSH Adult Male Rat |
| spellingShingle | Razieh Dehghanian Seyyed Ebrahim Hosseini Esfandiar Sharifi Davood Moghadamnia The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat Bihdād Taraxacum Officinale T3 T4 TSH Adult Male Rat |
| title | The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat |
| title_full | The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat |
| title_fullStr | The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat |
| title_full_unstemmed | The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat |
| title_short | The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat |
| title_sort | effects of taraxacum officinale alcoholic extract on serum thyroid hormone levels in adult male rat |
| topic | Taraxacum Officinale T3 T4 TSH Adult Male Rat |
| url | http://aums.abzums.ac.ir/browse.php?a_code=A-10-1-216&slc_lang=en&sid=1 |
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