Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers

Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers

The anticancer activities of Withaferin-A (Wi-A) and Withanone (Wi-N) from Ashwagandha and Caffeic Acid Phenethyl Ester (CAPE) from honeybee propolis have been well documented. Here, we examined the binding potential of these natural compounds to inhibit the constitutive phosphorylation of epidermal...

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Detalles Bibliográficos
Main Authors: Vidhi Malik, Vipul Kumar, Sunil C. Kaul, Renu Wadhwa, Durai Sundar
Formato: Artigo
Idioma:English
Publicado: MDPI AG 2021-01-01
Series:Biomolecules
Subjects:
EGFR
exon 20 insertion mutations
Withaferin A
Withanone
Caffeic Acid Phenethyl Ester
ATP competitive inhibitors
Acceso en liña:https://www.mdpi.com/2218-273X/11/2/160

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