Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers

Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers

The anticancer activities of Withaferin-A (Wi-A) and Withanone (Wi-N) from Ashwagandha and Caffeic Acid Phenethyl Ester (CAPE) from honeybee propolis have been well documented. Here, we examined the binding potential of these natural compounds to inhibit the constitutive phosphorylation of epidermal...

Полное описание

Библиографические подробности
Главные авторы:	Vidhi Malik, Vipul Kumar, Sunil C. Kaul, Renu Wadhwa, Durai Sundar
Формат:	Статья
Язык:	English
Опубликовано:	MDPI AG 2021-01-01
Серии:	Biomolecules
Предметы:	EGFR exon 20 insertion mutations Withaferin A Withanone Caffeic Acid Phenethyl Ester ATP competitive inhibitors
Online-ссылка:	https://www.mdpi.com/2218-273X/11/2/160

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