Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus

Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus

There are currently no approved treatments for Crimean-Congo Hemorrhagic Fever Virus (CCHFV) infection. In this study, the authors structurally characterize the epitope targeted by protective non-neutralizing mouse and human antibodies and provide insights into their broad range potential against va...

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Bibliographic Details
Main Authors: Ian A. Durie, Zahra R. Tehrani, Elif Karaaslan, Teresa E. Sorvillo, Jack McGuire, Joseph W. Golden, Stephen R. Welch, Markus H. Kainulainen, Jessica R. Harmon, Jarrod J. Mousa, David Gonzalez, Suzanne Enos, Iftihar Koksal, Gurdal Yilmaz, Hanife Nur Karakoc, Sanaz Hamidi, Cansu Albay, Jessica R. Spengler, Christina F. Spiropoulou, Aura R. Garrison, Mohammad M. Sajadi, Éric Bergeron, Scott D. Pegan
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34923-0

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