Frequency of Methicillin Resistance Among Staphylococcus aureus Clinical Isolates in Khartoum State, Sudan
Background: Methicillin-resistant Staphylococcus aureus (MRSA) have emerged as an important cause of nosocomial and community-acquired infections ranging from mild to severe life-threatening infections. Therefore, a reliable detection of such strains is required for effective treatment. Objec...
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| Format: | Article |
| Language: | English |
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Knowledge E
2018-12-01
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| Series: | Sudan Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.18502/sjms.v13i4.3596 |
| _version_ | 1818359091371704320 |
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| author | Najem Aldin Mohammed Osman Intisar Elhag Elraya Yassir Mahgoub Mohamed Muataz Mohamed Eldirdery Salaheldein Gumaa Elzaki Abdallah Elssir Ahmed and Ali Mohamed Elhassan Eleragi |
| author_facet | Najem Aldin Mohammed Osman Intisar Elhag Elraya Yassir Mahgoub Mohamed Muataz Mohamed Eldirdery Salaheldein Gumaa Elzaki Abdallah Elssir Ahmed and Ali Mohamed Elhassan Eleragi |
| author_sort | Najem Aldin Mohammed Osman |
| collection | DOAJ |
| description | Background: Methicillin-resistant Staphylococcus aureus (MRSA) have emerged as an important cause of nosocomial and community-acquired infections ranging from mild to severe life-threatening infections. Therefore, a reliable detection of such strains is required for effective treatment.
Objectives: To determine the frequency and the antibiogram of MRSA among different clinical isolates.
Study Design: A cross-sectional, descriptive study.
Materials and Methods: Standard bacteriological methods, disk diffusion and PCR were performed to determine the frequency of MRSA among different clinical isolates.
Results: The overall results showed 96/210 (45.7%) of isolates were MRSA mostly recovered from wounds and blood stream. High percentage was detected in hospital-associated (HA) strains (64.2%) rather than community (CA) (37.1%) (P-value < 0.001). From the generated Antibiogram, Co-trimoxazole was the most active (80.2%), while Penicillin was the least one (6.2%).
Conclusion: As MRSA strains were mostly isolated from Hospitals, clinicians should be aware of such burden strains. Local frequency investigation of MRSA is recommended for perfect diagnosis and treatment. |
| first_indexed | 2024-12-13T20:39:23Z |
| format | Article |
| id | doaj.art-ab18f686d48b43a5beda373cbb20912e |
| institution | Directory Open Access Journal |
| issn | 1858-5051 |
| language | English |
| last_indexed | 2024-12-13T20:39:23Z |
| publishDate | 2018-12-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Sudan Journal of Medical Sciences |
| spelling | doaj.art-ab18f686d48b43a5beda373cbb20912e2022-12-21T23:32:11ZengKnowledge ESudan Journal of Medical Sciences1858-50512018-12-01201711110.18502/sjms.v13i4.3596sjms.v13i4.3596Frequency of Methicillin Resistance Among Staphylococcus aureus Clinical Isolates in Khartoum State, SudanNajem Aldin Mohammed Osman0Intisar Elhag Elraya1Yassir Mahgoub Mohamed2Muataz Mohamed Eldirdery3Salaheldein Gumaa Elzaki4Abdallah Elssir Ahmed5and Ali Mohamed Elhassan Eleragi6 Department of Microbiology, Faculty of Medicine, University of Bisha, KSA Department of Microbiology, Faculty of Medicine, University of Bisha, KSA Department of Microbiology, Faculty of Medicine, University of Bisha, KSA Department of Microbiology, Faculty of Medicine, University of Bisha, KSA Department of Microbiology, Faculty of Medicine, University of Bisha, KSA Department of Microbiology, Faculty of Medicine, University of Bisha, KSA Department of Microbiology, Faculty of Medicine, University of Bisha, KSABackground: Methicillin-resistant Staphylococcus aureus (MRSA) have emerged as an important cause of nosocomial and community-acquired infections ranging from mild to severe life-threatening infections. Therefore, a reliable detection of such strains is required for effective treatment. Objectives: To determine the frequency and the antibiogram of MRSA among different clinical isolates. Study Design: A cross-sectional, descriptive study. Materials and Methods: Standard bacteriological methods, disk diffusion and PCR were performed to determine the frequency of MRSA among different clinical isolates. Results: The overall results showed 96/210 (45.7%) of isolates were MRSA mostly recovered from wounds and blood stream. High percentage was detected in hospital-associated (HA) strains (64.2%) rather than community (CA) (37.1%) (P-value < 0.001). From the generated Antibiogram, Co-trimoxazole was the most active (80.2%), while Penicillin was the least one (6.2%). Conclusion: As MRSA strains were mostly isolated from Hospitals, clinicians should be aware of such burden strains. Local frequency investigation of MRSA is recommended for perfect diagnosis and treatment.https://doi.org/10.18502/sjms.v13i4.3596MRSA, S. aureus, mecA, Sudan |
| spellingShingle | Najem Aldin Mohammed Osman Intisar Elhag Elraya Yassir Mahgoub Mohamed Muataz Mohamed Eldirdery Salaheldein Gumaa Elzaki Abdallah Elssir Ahmed and Ali Mohamed Elhassan Eleragi Frequency of Methicillin Resistance Among Staphylococcus aureus Clinical Isolates in Khartoum State, Sudan Sudan Journal of Medical Sciences MRSA, S. aureus, mecA, Sudan |
| title | Frequency of Methicillin Resistance Among Staphylococcus aureus Clinical Isolates in Khartoum State, Sudan |
| title_full | Frequency of Methicillin Resistance Among Staphylococcus aureus Clinical Isolates in Khartoum State, Sudan |
| title_fullStr | Frequency of Methicillin Resistance Among Staphylococcus aureus Clinical Isolates in Khartoum State, Sudan |
| title_full_unstemmed | Frequency of Methicillin Resistance Among Staphylococcus aureus Clinical Isolates in Khartoum State, Sudan |
| title_short | Frequency of Methicillin Resistance Among Staphylococcus aureus Clinical Isolates in Khartoum State, Sudan |
| title_sort | frequency of methicillin resistance among staphylococcus aureus clinical isolates in khartoum state sudan |
| topic | MRSA, S. aureus, mecA, Sudan |
| url | https://doi.org/10.18502/sjms.v13i4.3596 |
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