Necrotising soft tissue infection in the present era: an analysis of clinicopathological features and predictors of mortality
Background: Necrotizing soft tissue infections (NSTI) and non-NSTI are frequently difficult to distinguish based on symptoms, signs, and investigations. High morbidity related to it can only be avoided by early detection and treatment. Aim: This study examined demographic, clinicopathological, NSTI...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-06-01
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| Series: | Surgery in Practice and Science |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666262023000098 |
| _version_ | 1827931786150150144 |
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| author | Dr Alok Anshu Dr Surjeet Dwivedi Dr M Murali Dr Harsha MP |
| author_facet | Dr Alok Anshu Dr Surjeet Dwivedi Dr M Murali Dr Harsha MP |
| author_sort | Dr Alok Anshu |
| collection | DOAJ |
| description | Background: Necrotizing soft tissue infections (NSTI) and non-NSTI are frequently difficult to distinguish based on symptoms, signs, and investigations. High morbidity related to it can only be avoided by early detection and treatment. Aim: This study examined demographic, clinicopathological, NSTI prognosis, and mortality factors. Methodology: 80 NSTI patients were retrospectively studied. Clinicopathological profile, surgical management, histological report, and LRINEC score were included. Mortality predictions were evaluated between survivors and non-survivors. Results: 73.8 percent of patients were male and the mean age was 55.4±9.6 years. Nonsurvivors averaged 11.88±0.72 LRINEC scores. Non-survivor CRP averaged 236.5±48.5 mg/l. Gp A Hemolytic Streptococci were most frequent (37.8 percent ). Diabetes was a significant mortality predictor. Total mortality was 20%. Conclusion: NSTI remains a major killer. High mortality is linked to age, diabetes, higher blood creatinine, MODS, and delayed surgery.” and proceed accordingly. |
| first_indexed | 2024-03-13T06:58:11Z |
| format | Article |
| id | doaj.art-ab1a1d99e0c14882a8a9901f0e489d4c |
| institution | Directory Open Access Journal |
| issn | 2666-2620 |
| language | English |
| last_indexed | 2024-03-13T06:58:11Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Surgery in Practice and Science |
| spelling | doaj.art-ab1a1d99e0c14882a8a9901f0e489d4c2023-06-07T04:49:46ZengElsevierSurgery in Practice and Science2666-26202023-06-0113100163Necrotising soft tissue infection in the present era: an analysis of clinicopathological features and predictors of mortalityDr Alok Anshu0Dr Surjeet Dwivedi1Dr M Murali2Dr Harsha MP3Dept of Surgery, 7 Air Force Hospital, Kanpur, India; Corresponding author.DNB Oncosurgery, Dept of Oncosurgery, Command Hospital Air Force, Bangalore, IndiaDy Principal Medical Officer, Training Command, Bangalore, IndiaDept of Surgery, Command Hospital Kolkata, IndiaBackground: Necrotizing soft tissue infections (NSTI) and non-NSTI are frequently difficult to distinguish based on symptoms, signs, and investigations. High morbidity related to it can only be avoided by early detection and treatment. Aim: This study examined demographic, clinicopathological, NSTI prognosis, and mortality factors. Methodology: 80 NSTI patients were retrospectively studied. Clinicopathological profile, surgical management, histological report, and LRINEC score were included. Mortality predictions were evaluated between survivors and non-survivors. Results: 73.8 percent of patients were male and the mean age was 55.4±9.6 years. Nonsurvivors averaged 11.88±0.72 LRINEC scores. Non-survivor CRP averaged 236.5±48.5 mg/l. Gp A Hemolytic Streptococci were most frequent (37.8 percent ). Diabetes was a significant mortality predictor. Total mortality was 20%. Conclusion: NSTI remains a major killer. High mortality is linked to age, diabetes, higher blood creatinine, MODS, and delayed surgery.” and proceed accordingly.http://www.sciencedirect.com/science/article/pii/S2666262023000098 |
| spellingShingle | Dr Alok Anshu Dr Surjeet Dwivedi Dr M Murali Dr Harsha MP Necrotising soft tissue infection in the present era: an analysis of clinicopathological features and predictors of mortality Surgery in Practice and Science |
| title | Necrotising soft tissue infection in the present era: an analysis of clinicopathological features and predictors of mortality |
| title_full | Necrotising soft tissue infection in the present era: an analysis of clinicopathological features and predictors of mortality |
| title_fullStr | Necrotising soft tissue infection in the present era: an analysis of clinicopathological features and predictors of mortality |
| title_full_unstemmed | Necrotising soft tissue infection in the present era: an analysis of clinicopathological features and predictors of mortality |
| title_short | Necrotising soft tissue infection in the present era: an analysis of clinicopathological features and predictors of mortality |
| title_sort | necrotising soft tissue infection in the present era an analysis of clinicopathological features and predictors of mortality |
| url | http://www.sciencedirect.com/science/article/pii/S2666262023000098 |
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