Bone fluorescence and fluorescence-guided debridement in orthopaedic surgery: Current evidence and practice
Introduction: The present manuscript discusses the basic science of bone fluorescence and the surgical debridement of chronic osteomyelitis under fluorescence-guidance. The fluorescence of bone occurs through a two-fold mechanism: natural fluorescence of collagen peptides within healthy bone and tet...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Journal of Orthopaedic Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773157X2200128X |
| _version_ | 1811168421734252544 |
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| author | Garrhett G. Via Jennifer L. Jerele |
| author_facet | Garrhett G. Via Jennifer L. Jerele |
| author_sort | Garrhett G. Via |
| collection | DOAJ |
| description | Introduction: The present manuscript discusses the basic science of bone fluorescence and the surgical debridement of chronic osteomyelitis under fluorescence-guidance. The fluorescence of bone occurs through a two-fold mechanism: natural fluorescence of collagen peptides within healthy bone and tetracycline bone labeling. Objective: The manuscript addresses mechanisms for natural bone fluorescence, enhancing fluorescence via tetracycline labeling, as well as a brief description of applications to orthopaedic surgery. Conclusion: This review provides the most recent literature on the topic and describes the practical implications on modern surgery techniques. |
| first_indexed | 2024-04-10T16:27:10Z |
| format | Article |
| id | doaj.art-ab1dbede7dd640538226397b1167fb94 |
| institution | Directory Open Access Journal |
| issn | 2773-157X |
| language | English |
| last_indexed | 2024-04-10T16:27:10Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Orthopaedic Reports |
| spelling | doaj.art-ab1dbede7dd640538226397b1167fb942023-02-09T04:15:07ZengElsevierJournal of Orthopaedic Reports2773-157X2023-01-0121100120Bone fluorescence and fluorescence-guided debridement in orthopaedic surgery: Current evidence and practiceGarrhett G. Via0Jennifer L. Jerele1Corresponding author. 30 E. Apple St., Ste 2200, Dayton, OH, 45409, USA.; Wright State University Department of Orthopaedic Surgery, 30 E. Apple St., Ste 2200, Dayton, OH, 45409, USAWright State University Department of Orthopaedic Surgery, 30 E. Apple St., Ste 2200, Dayton, OH, 45409, USAIntroduction: The present manuscript discusses the basic science of bone fluorescence and the surgical debridement of chronic osteomyelitis under fluorescence-guidance. The fluorescence of bone occurs through a two-fold mechanism: natural fluorescence of collagen peptides within healthy bone and tetracycline bone labeling. Objective: The manuscript addresses mechanisms for natural bone fluorescence, enhancing fluorescence via tetracycline labeling, as well as a brief description of applications to orthopaedic surgery. Conclusion: This review provides the most recent literature on the topic and describes the practical implications on modern surgery techniques.http://www.sciencedirect.com/science/article/pii/S2773157X2200128XBoneFluorescenceDoxycyclineOsteomyelitisBone labelingCollagen |
| spellingShingle | Garrhett G. Via Jennifer L. Jerele Bone fluorescence and fluorescence-guided debridement in orthopaedic surgery: Current evidence and practice Journal of Orthopaedic Reports Bone Fluorescence Doxycycline Osteomyelitis Bone labeling Collagen |
| title | Bone fluorescence and fluorescence-guided debridement in orthopaedic surgery: Current evidence and practice |
| title_full | Bone fluorescence and fluorescence-guided debridement in orthopaedic surgery: Current evidence and practice |
| title_fullStr | Bone fluorescence and fluorescence-guided debridement in orthopaedic surgery: Current evidence and practice |
| title_full_unstemmed | Bone fluorescence and fluorescence-guided debridement in orthopaedic surgery: Current evidence and practice |
| title_short | Bone fluorescence and fluorescence-guided debridement in orthopaedic surgery: Current evidence and practice |
| title_sort | bone fluorescence and fluorescence guided debridement in orthopaedic surgery current evidence and practice |
| topic | Bone Fluorescence Doxycycline Osteomyelitis Bone labeling Collagen |
| url | http://www.sciencedirect.com/science/article/pii/S2773157X2200128X |
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