Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan

An efficient multi-component synthesis of dihydrofurans is described by a one-pot condensation reaction of 2,4′-dibromoacetophenone, aromatic aldehydes and dimedone using nano-CuFe2O4@Chitosan under reflux conditions in ethanol. The key advantages of this process are the diastereoselective synthesis...

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Bibliographic Details
Main Authors: Javad Safaei-Ghomi, Hossein Shahbazi-Alavi
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Saudi Chemical Society
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610317300376
Description
Summary:An efficient multi-component synthesis of dihydrofurans is described by a one-pot condensation reaction of 2,4′-dibromoacetophenone, aromatic aldehydes and dimedone using nano-CuFe2O4@Chitosan under reflux conditions in ethanol. The key advantages of this process are the diastereoselective synthesis, low catalyst loading, reusability of the catalyst, excellent yields, short reaction times, simple workup and environmentally benign. Keywords: Nano-CuFe2O4@Chitosan, Nanocatalyst, Dihydrofurans, Diastereoselective synthesis, One-pot
ISSN:1319-6103