Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan
An efficient multi-component synthesis of dihydrofurans is described by a one-pot condensation reaction of 2,4′-dibromoacetophenone, aromatic aldehydes and dimedone using nano-CuFe2O4@Chitosan under reflux conditions in ethanol. The key advantages of this process are the diastereoselective synthesis...
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Format: | Article |
Language: | English |
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Elsevier
2017-09-01
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Series: | Journal of Saudi Chemical Society |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319610317300376 |
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author | Javad Safaei-Ghomi Hossein Shahbazi-Alavi |
author_facet | Javad Safaei-Ghomi Hossein Shahbazi-Alavi |
author_sort | Javad Safaei-Ghomi |
collection | DOAJ |
description | An efficient multi-component synthesis of dihydrofurans is described by a one-pot condensation reaction of 2,4′-dibromoacetophenone, aromatic aldehydes and dimedone using nano-CuFe2O4@Chitosan under reflux conditions in ethanol. The key advantages of this process are the diastereoselective synthesis, low catalyst loading, reusability of the catalyst, excellent yields, short reaction times, simple workup and environmentally benign. Keywords: Nano-CuFe2O4@Chitosan, Nanocatalyst, Dihydrofurans, Diastereoselective synthesis, One-pot |
first_indexed | 2024-04-12T08:54:16Z |
format | Article |
id | doaj.art-ab1e0fb0ed304230946390b2d207ce07 |
institution | Directory Open Access Journal |
issn | 1319-6103 |
language | English |
last_indexed | 2024-04-12T08:54:16Z |
publishDate | 2017-09-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Saudi Chemical Society |
spelling | doaj.art-ab1e0fb0ed304230946390b2d207ce072022-12-22T03:39:30ZengElsevierJournal of Saudi Chemical Society1319-61032017-09-01216698707Synthesis of dihydrofurans using nano-CuFe2O4@ChitosanJavad Safaei-Ghomi0Hossein Shahbazi-Alavi1Corresponding author. Fax: +98 31 55912397.; Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, P.O. Box 87317-51167, Kashan, Islamic Republic of IranDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, P.O. Box 87317-51167, Kashan, Islamic Republic of IranAn efficient multi-component synthesis of dihydrofurans is described by a one-pot condensation reaction of 2,4′-dibromoacetophenone, aromatic aldehydes and dimedone using nano-CuFe2O4@Chitosan under reflux conditions in ethanol. The key advantages of this process are the diastereoselective synthesis, low catalyst loading, reusability of the catalyst, excellent yields, short reaction times, simple workup and environmentally benign. Keywords: Nano-CuFe2O4@Chitosan, Nanocatalyst, Dihydrofurans, Diastereoselective synthesis, One-pothttp://www.sciencedirect.com/science/article/pii/S1319610317300376 |
spellingShingle | Javad Safaei-Ghomi Hossein Shahbazi-Alavi Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan Journal of Saudi Chemical Society |
title | Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan |
title_full | Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan |
title_fullStr | Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan |
title_full_unstemmed | Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan |
title_short | Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan |
title_sort | synthesis of dihydrofurans using nano cufe2o4 chitosan |
url | http://www.sciencedirect.com/science/article/pii/S1319610317300376 |
work_keys_str_mv | AT javadsafaeighomi synthesisofdihydrofuransusingnanocufe2o4chitosan AT hosseinshahbazialavi synthesisofdihydrofuransusingnanocufe2o4chitosan |