Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan

An efficient multi-component synthesis of dihydrofurans is described by a one-pot condensation reaction of 2,4′-dibromoacetophenone, aromatic aldehydes and dimedone using nano-CuFe2O4@Chitosan under reflux conditions in ethanol. The key advantages of this process are the diastereoselective synthesis...

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Main Authors: Javad Safaei-Ghomi, Hossein Shahbazi-Alavi
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Saudi Chemical Society
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610317300376
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author Javad Safaei-Ghomi
Hossein Shahbazi-Alavi
author_facet Javad Safaei-Ghomi
Hossein Shahbazi-Alavi
author_sort Javad Safaei-Ghomi
collection DOAJ
description An efficient multi-component synthesis of dihydrofurans is described by a one-pot condensation reaction of 2,4′-dibromoacetophenone, aromatic aldehydes and dimedone using nano-CuFe2O4@Chitosan under reflux conditions in ethanol. The key advantages of this process are the diastereoselective synthesis, low catalyst loading, reusability of the catalyst, excellent yields, short reaction times, simple workup and environmentally benign. Keywords: Nano-CuFe2O4@Chitosan, Nanocatalyst, Dihydrofurans, Diastereoselective synthesis, One-pot
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spelling doaj.art-ab1e0fb0ed304230946390b2d207ce072022-12-22T03:39:30ZengElsevierJournal of Saudi Chemical Society1319-61032017-09-01216698707Synthesis of dihydrofurans using nano-CuFe2O4@ChitosanJavad Safaei-Ghomi0Hossein Shahbazi-Alavi1Corresponding author. Fax: +98 31 55912397.; Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, P.O. Box 87317-51167, Kashan, Islamic Republic of IranDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, P.O. Box 87317-51167, Kashan, Islamic Republic of IranAn efficient multi-component synthesis of dihydrofurans is described by a one-pot condensation reaction of 2,4′-dibromoacetophenone, aromatic aldehydes and dimedone using nano-CuFe2O4@Chitosan under reflux conditions in ethanol. The key advantages of this process are the diastereoselective synthesis, low catalyst loading, reusability of the catalyst, excellent yields, short reaction times, simple workup and environmentally benign. Keywords: Nano-CuFe2O4@Chitosan, Nanocatalyst, Dihydrofurans, Diastereoselective synthesis, One-pothttp://www.sciencedirect.com/science/article/pii/S1319610317300376
spellingShingle Javad Safaei-Ghomi
Hossein Shahbazi-Alavi
Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan
Journal of Saudi Chemical Society
title Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan
title_full Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan
title_fullStr Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan
title_full_unstemmed Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan
title_short Synthesis of dihydrofurans using nano-CuFe2O4@Chitosan
title_sort synthesis of dihydrofurans using nano cufe2o4 chitosan
url http://www.sciencedirect.com/science/article/pii/S1319610317300376
work_keys_str_mv AT javadsafaeighomi synthesisofdihydrofuransusingnanocufe2o4chitosan
AT hosseinshahbazialavi synthesisofdihydrofuransusingnanocufe2o4chitosan