Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study
Introduction: Intrauterine fetal death (IUFD) is defined as death of the fetus after the 20th week of gestation. Despite regular monitoring the incidence of IUFD remains high. This study aims to assess the incidence and maternal conditions associated with IUFD over term pregnancies in a twelve-year...
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MDPI AG
2023-12-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/12/2320 |
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| author | Ivana Jovanovic Katarina Ivanovic Sanja Kostic Jasmina Tadic Stefan Dugalic Milica Petronijevic Miroslava Gojnic Miloš Petronijevic Svetlana Vrzic-Petronijevic |
| author_facet | Ivana Jovanovic Katarina Ivanovic Sanja Kostic Jasmina Tadic Stefan Dugalic Milica Petronijevic Miroslava Gojnic Miloš Petronijevic Svetlana Vrzic-Petronijevic |
| author_sort | Ivana Jovanovic |
| collection | DOAJ |
| description | Introduction: Intrauterine fetal death (IUFD) is defined as death of the fetus after the 20th week of gestation. Despite regular monitoring the incidence of IUFD remains high. This study aims to assess the incidence and maternal conditions associated with IUFD over term pregnancies in a twelve-year period. Materials and Methods: A retrospective descriptive study was conducted on a population of women in whom IUFD was diagnosed in a term pregnancy during the period from January 2010 to December 2022. The study was at the Clinic for Obstetrics and Gynecology, University Clinic Centre of Serbia. The analyses included the number of deliveries, live births, and stillbirths, as well as maternal, fetal, and placental conditions associated with the risk of IUDF. The statistical analysis involved descriptive statistical methods and one sample proportion. Results: The average age of the patients was 30 years. Most patients had secondary and higher education, and 70% of patients had regular pregnancy monitoring; 53.33% were primiparous and pregnancies occurred spontaneously. IUFD mainly occurred in the 39th week of gestation. In total, 38.3% had one to two associated diseases, 5% more than three, and 58.33% were healthy. Recurrence of IUFD was reported by 10% of patients, while 8.33% had a history of spontaneous abortion. Over 80% of placental histopathological findings indicated some pathology (e.g., infarction, infections, placental abruption). Conclusions: The most significant risk factors for IUFD in term pregnancies in our population during the study period were hypertensive syndrome in pregnancy, obesity and gestational diabetes. Pathological findings on the placenta were more common in our study group than is usually reported with infractions of placental tissue being the most common, even in healthy women. |
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| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-08T20:36:06Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-ab1f44faa92c42b0a99e97ae99dc80a62023-12-22T14:21:18ZengMDPI AGLife2075-17292023-12-011312232010.3390/life13122320Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic StudyIvana Jovanovic0Katarina Ivanovic1Sanja Kostic2Jasmina Tadic3Stefan Dugalic4Milica Petronijevic5Miroslava Gojnic6Miloš Petronijevic7Svetlana Vrzic-Petronijevic8Faculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaClinic for Obstetrics and Gynecology, University Clinical Centre of Serbia, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaIntroduction: Intrauterine fetal death (IUFD) is defined as death of the fetus after the 20th week of gestation. Despite regular monitoring the incidence of IUFD remains high. This study aims to assess the incidence and maternal conditions associated with IUFD over term pregnancies in a twelve-year period. Materials and Methods: A retrospective descriptive study was conducted on a population of women in whom IUFD was diagnosed in a term pregnancy during the period from January 2010 to December 2022. The study was at the Clinic for Obstetrics and Gynecology, University Clinic Centre of Serbia. The analyses included the number of deliveries, live births, and stillbirths, as well as maternal, fetal, and placental conditions associated with the risk of IUDF. The statistical analysis involved descriptive statistical methods and one sample proportion. Results: The average age of the patients was 30 years. Most patients had secondary and higher education, and 70% of patients had regular pregnancy monitoring; 53.33% were primiparous and pregnancies occurred spontaneously. IUFD mainly occurred in the 39th week of gestation. In total, 38.3% had one to two associated diseases, 5% more than three, and 58.33% were healthy. Recurrence of IUFD was reported by 10% of patients, while 8.33% had a history of spontaneous abortion. Over 80% of placental histopathological findings indicated some pathology (e.g., infarction, infections, placental abruption). Conclusions: The most significant risk factors for IUFD in term pregnancies in our population during the study period were hypertensive syndrome in pregnancy, obesity and gestational diabetes. Pathological findings on the placenta were more common in our study group than is usually reported with infractions of placental tissue being the most common, even in healthy women.https://www.mdpi.com/2075-1729/13/12/2320intrauterine fetal deathterm pregnancies |
| spellingShingle | Ivana Jovanovic Katarina Ivanovic Sanja Kostic Jasmina Tadic Stefan Dugalic Milica Petronijevic Miroslava Gojnic Miloš Petronijevic Svetlana Vrzic-Petronijevic Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study Life intrauterine fetal death term pregnancies |
| title | Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study |
| title_full | Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study |
| title_fullStr | Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study |
| title_full_unstemmed | Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study |
| title_short | Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study |
| title_sort | intrauterine fetal death in term pregnancy a single tertiary clinic study |
| topic | intrauterine fetal death term pregnancies |
| url | https://www.mdpi.com/2075-1729/13/12/2320 |
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