Ocular adverse effects of therapeutic biologics
Biological drugs, termed biologics, are medications that contain or are derived from a living organism (human, animal, or microorganism). With new biological agents being approved by the Food and Drug Administration (FDA) every year, clinicians need to know potential ocular adverse effects that are...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-04-01
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| Series: | Therapeutic Advances in Ophthalmology |
| Online Access: | https://doi.org/10.1177/25158414211070878 |
| _version_ | 1817993566627037184 |
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| author | Helio V. Neves da Silva John Placide Anne Duong Yasmyne Ronquillo Shannon McCabe Majid Moshirfar |
| author_facet | Helio V. Neves da Silva John Placide Anne Duong Yasmyne Ronquillo Shannon McCabe Majid Moshirfar |
| author_sort | Helio V. Neves da Silva |
| collection | DOAJ |
| description | Biological drugs, termed biologics, are medications that contain or are derived from a living organism (human, animal, or microorganism). With new biological agents being approved by the Food and Drug Administration (FDA) every year, clinicians need to know potential ocular adverse effects that are associated with these drugs. This review provides an overview of ocular adverse effects of biological medications used to treat both ophthalmic and non-ophthalmic diseases. We searched PubMed for relevant case reports, case series, reviews, and clinical trials reporting ocular adverse effects caused by biologics. This review was conducted in June 2021 and investigated the drugs listed in the most updated (April 2021) FDA Purple Book Database of Licensed Biological Products. This review focuses on monoclonal antibodies, interleukins, and receptor fusion proteins. We explore ocular side effects of 33 biological drugs, stating whether they are frequent, common, or rare. |
| first_indexed | 2024-04-14T01:41:38Z |
| format | Article |
| id | doaj.art-ab1fb3454a164aa38b73427181198cf3 |
| institution | Directory Open Access Journal |
| issn | 2515-8414 |
| language | English |
| last_indexed | 2024-04-14T01:41:38Z |
| publishDate | 2022-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Ophthalmology |
| spelling | doaj.art-ab1fb3454a164aa38b73427181198cf32022-12-22T02:19:45ZengSAGE PublishingTherapeutic Advances in Ophthalmology2515-84142022-04-011410.1177/25158414211070878Ocular adverse effects of therapeutic biologicsHelio V. Neves da SilvaJohn PlacideAnne DuongYasmyne RonquilloShannon McCabeMajid MoshirfarBiological drugs, termed biologics, are medications that contain or are derived from a living organism (human, animal, or microorganism). With new biological agents being approved by the Food and Drug Administration (FDA) every year, clinicians need to know potential ocular adverse effects that are associated with these drugs. This review provides an overview of ocular adverse effects of biological medications used to treat both ophthalmic and non-ophthalmic diseases. We searched PubMed for relevant case reports, case series, reviews, and clinical trials reporting ocular adverse effects caused by biologics. This review was conducted in June 2021 and investigated the drugs listed in the most updated (April 2021) FDA Purple Book Database of Licensed Biological Products. This review focuses on monoclonal antibodies, interleukins, and receptor fusion proteins. We explore ocular side effects of 33 biological drugs, stating whether they are frequent, common, or rare.https://doi.org/10.1177/25158414211070878 |
| spellingShingle | Helio V. Neves da Silva John Placide Anne Duong Yasmyne Ronquillo Shannon McCabe Majid Moshirfar Ocular adverse effects of therapeutic biologics Therapeutic Advances in Ophthalmology |
| title | Ocular adverse effects of therapeutic biologics |
| title_full | Ocular adverse effects of therapeutic biologics |
| title_fullStr | Ocular adverse effects of therapeutic biologics |
| title_full_unstemmed | Ocular adverse effects of therapeutic biologics |
| title_short | Ocular adverse effects of therapeutic biologics |
| title_sort | ocular adverse effects of therapeutic biologics |
| url | https://doi.org/10.1177/25158414211070878 |
| work_keys_str_mv | AT heliovnevesdasilva ocularadverseeffectsoftherapeuticbiologics AT johnplacide ocularadverseeffectsoftherapeuticbiologics AT anneduong ocularadverseeffectsoftherapeuticbiologics AT yasmyneronquillo ocularadverseeffectsoftherapeuticbiologics AT shannonmccabe ocularadverseeffectsoftherapeuticbiologics AT majidmoshirfar ocularadverseeffectsoftherapeuticbiologics |