Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer

Prostate cancer is the second most common cancer in men, with 1.1 million new cases worldwide reported by the World Health Organization in one recent year. Transrectal ultrasound (TRUS)-guided biopsy has been used for the diagnosis of prostate cancer for over 2 decades, but the technique is usually...

Full description

Bibliographic Details
Main Authors: Jesse D Le, Jiaoti Huang, Leonard S Marks
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-08-01
Series:Asian Journal of Andrology
Subjects:
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=522;epage=529;aulast=Le
_version_ 1818154408286879744
author Jesse D Le
Jiaoti Huang
Leonard S Marks
author_facet Jesse D Le
Jiaoti Huang
Leonard S Marks
author_sort Jesse D Le
collection DOAJ
description Prostate cancer is the second most common cancer in men, with 1.1 million new cases worldwide reported by the World Health Organization in one recent year. Transrectal ultrasound (TRUS)-guided biopsy has been used for the diagnosis of prostate cancer for over 2 decades, but the technique is usually blind to cancer location. Moreover, the false negative rate of TRUS biopsy has been reported to be as high as 47%. Multiparametric magnetic resonance imaging (mp-MRI) includes T1- and T2-weighted imaging as well as dynamic contrast-enhanced (DCE) and diffusion-weighted imaging (DWI). mp-MRI is a major advance in the imaging of prostate cancer, enabling targeted biopsy of suspicious lesions. Evolving targeted biopsy techniques-including direct in-bore biopsy, cognitive fusion and software-based MRI-ultrasound (MRI-US) fusion-have led to a several-fold improvement in cancer detection compared to the earlier method. Importantly, the detection of clinically significant cancers has been greatly facilitated by targeting, compared to systematic biopsy alone. Targeted biopsy via MRI-US fusion may dramatically alter the way prostate cancer is diagnosed and managed.
first_indexed 2024-12-11T14:26:02Z
format Article
id doaj.art-ab1fc7af2d1843a68d78ef2b87fe8503
institution Directory Open Access Journal
issn 1008-682X
1745-7262
language English
last_indexed 2024-12-11T14:26:02Z
publishDate 2014-08-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Asian Journal of Andrology
spelling doaj.art-ab1fc7af2d1843a68d78ef2b87fe85032022-12-22T01:02:40ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622014-08-0116452252910.4103/1008-682X.122864Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancerJesse D LeJiaoti HuangLeonard S MarksProstate cancer is the second most common cancer in men, with 1.1 million new cases worldwide reported by the World Health Organization in one recent year. Transrectal ultrasound (TRUS)-guided biopsy has been used for the diagnosis of prostate cancer for over 2 decades, but the technique is usually blind to cancer location. Moreover, the false negative rate of TRUS biopsy has been reported to be as high as 47%. Multiparametric magnetic resonance imaging (mp-MRI) includes T1- and T2-weighted imaging as well as dynamic contrast-enhanced (DCE) and diffusion-weighted imaging (DWI). mp-MRI is a major advance in the imaging of prostate cancer, enabling targeted biopsy of suspicious lesions. Evolving targeted biopsy techniques-including direct in-bore biopsy, cognitive fusion and software-based MRI-ultrasound (MRI-US) fusion-have led to a several-fold improvement in cancer detection compared to the earlier method. Importantly, the detection of clinically significant cancers has been greatly facilitated by targeting, compared to systematic biopsy alone. Targeted biopsy via MRI-US fusion may dramatically alter the way prostate cancer is diagnosed and managed.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=522;epage=529;aulast=Lefusion biopsy; magnetic resonance imaging (MRI); prostate biopsy; prostate cancer; targeted biopsy; ultrasound
spellingShingle Jesse D Le
Jiaoti Huang
Leonard S Marks
Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer
Asian Journal of Andrology
fusion biopsy; magnetic resonance imaging (MRI); prostate biopsy; prostate cancer; targeted biopsy; ultrasound
title Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer
title_full Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer
title_fullStr Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer
title_full_unstemmed Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer
title_short Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer
title_sort targeted prostate biopsy value of multiparametric magnetic resonance imaging in detection of localized cancer
topic fusion biopsy; magnetic resonance imaging (MRI); prostate biopsy; prostate cancer; targeted biopsy; ultrasound
url http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=522;epage=529;aulast=Le
work_keys_str_mv AT jessedle targetedprostatebiopsyvalueofmultiparametricmagneticresonanceimagingindetectionoflocalizedcancer
AT jiaotihuang targetedprostatebiopsyvalueofmultiparametricmagneticresonanceimagingindetectionoflocalizedcancer
AT leonardsmarks targetedprostatebiopsyvalueofmultiparametricmagneticresonanceimagingindetectionoflocalizedcancer