Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer
Prostate cancer is the second most common cancer in men, with 1.1 million new cases worldwide reported by the World Health Organization in one recent year. Transrectal ultrasound (TRUS)-guided biopsy has been used for the diagnosis of prostate cancer for over 2 decades, but the technique is usually...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2014-08-01
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Series: | Asian Journal of Andrology |
Subjects: | |
Online Access: | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=522;epage=529;aulast=Le |
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author | Jesse D Le Jiaoti Huang Leonard S Marks |
author_facet | Jesse D Le Jiaoti Huang Leonard S Marks |
author_sort | Jesse D Le |
collection | DOAJ |
description | Prostate cancer is the second most common cancer in men, with 1.1 million new cases worldwide reported by the World Health Organization in one recent year. Transrectal ultrasound (TRUS)-guided biopsy has been used for the diagnosis of prostate cancer for over 2 decades, but the technique is usually blind to cancer location. Moreover, the false negative rate of TRUS biopsy has been reported to be as high as 47%. Multiparametric magnetic resonance imaging (mp-MRI) includes T1- and T2-weighted imaging as well as dynamic contrast-enhanced (DCE) and diffusion-weighted imaging (DWI). mp-MRI is a major advance in the imaging of prostate cancer, enabling targeted biopsy of suspicious lesions. Evolving targeted biopsy techniques-including direct in-bore biopsy, cognitive fusion and software-based MRI-ultrasound (MRI-US) fusion-have led to a several-fold improvement in cancer detection compared to the earlier method. Importantly, the detection of clinically significant cancers has been greatly facilitated by targeting, compared to systematic biopsy alone. Targeted biopsy via MRI-US fusion may dramatically alter the way prostate cancer is diagnosed and managed. |
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format | Article |
id | doaj.art-ab1fc7af2d1843a68d78ef2b87fe8503 |
institution | Directory Open Access Journal |
issn | 1008-682X 1745-7262 |
language | English |
last_indexed | 2024-12-11T14:26:02Z |
publishDate | 2014-08-01 |
publisher | Wolters Kluwer Medknow Publications |
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series | Asian Journal of Andrology |
spelling | doaj.art-ab1fc7af2d1843a68d78ef2b87fe85032022-12-22T01:02:40ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622014-08-0116452252910.4103/1008-682X.122864Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancerJesse D LeJiaoti HuangLeonard S MarksProstate cancer is the second most common cancer in men, with 1.1 million new cases worldwide reported by the World Health Organization in one recent year. Transrectal ultrasound (TRUS)-guided biopsy has been used for the diagnosis of prostate cancer for over 2 decades, but the technique is usually blind to cancer location. Moreover, the false negative rate of TRUS biopsy has been reported to be as high as 47%. Multiparametric magnetic resonance imaging (mp-MRI) includes T1- and T2-weighted imaging as well as dynamic contrast-enhanced (DCE) and diffusion-weighted imaging (DWI). mp-MRI is a major advance in the imaging of prostate cancer, enabling targeted biopsy of suspicious lesions. Evolving targeted biopsy techniques-including direct in-bore biopsy, cognitive fusion and software-based MRI-ultrasound (MRI-US) fusion-have led to a several-fold improvement in cancer detection compared to the earlier method. Importantly, the detection of clinically significant cancers has been greatly facilitated by targeting, compared to systematic biopsy alone. Targeted biopsy via MRI-US fusion may dramatically alter the way prostate cancer is diagnosed and managed.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=522;epage=529;aulast=Lefusion biopsy; magnetic resonance imaging (MRI); prostate biopsy; prostate cancer; targeted biopsy; ultrasound |
spellingShingle | Jesse D Le Jiaoti Huang Leonard S Marks Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer Asian Journal of Andrology fusion biopsy; magnetic resonance imaging (MRI); prostate biopsy; prostate cancer; targeted biopsy; ultrasound |
title | Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer |
title_full | Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer |
title_fullStr | Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer |
title_full_unstemmed | Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer |
title_short | Targeted prostate biopsy: value of multiparametric magnetic resonance imaging in detection of localized cancer |
title_sort | targeted prostate biopsy value of multiparametric magnetic resonance imaging in detection of localized cancer |
topic | fusion biopsy; magnetic resonance imaging (MRI); prostate biopsy; prostate cancer; targeted biopsy; ultrasound |
url | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=522;epage=529;aulast=Le |
work_keys_str_mv | AT jessedle targetedprostatebiopsyvalueofmultiparametricmagneticresonanceimagingindetectionoflocalizedcancer AT jiaotihuang targetedprostatebiopsyvalueofmultiparametricmagneticresonanceimagingindetectionoflocalizedcancer AT leonardsmarks targetedprostatebiopsyvalueofmultiparametricmagneticresonanceimagingindetectionoflocalizedcancer |