WIPI-Mediated Autophagy and Longevity

WIPI-Mediated Autophagy and Longevity

Autophagy is a lysosomal degradation process for cytoplasmic components, including organelles, membranes, and proteins, and critically secures eukaryotic cellular homeostasis and survival. Moreover, autophagy-related (ATG) genes are considered essential for longevity control in model organisms. Cent...

Full description

Bibliographic Details
Main Authors:	Mona Grimmel, Charlotte Backhaus, Tassula Proikas-Cezanne
Format:	Article
Language:	English
Published:	MDPI AG 2015-05-01
Series:	Cells
Subjects:	autophagy longevity WIPI WIPI-1 WIPI-2 ATG-18 EPG-6 C. elegans
Online Access:	http://www.mdpi.com/2073-4409/4/2/202

Similar Items

ATG-18 and EPG-6 are Both Required for Autophagy but Differentially Contribute to Lifespan Control in Caenorhabditis elegans
by: Zsuzsanna Takacs, et al.
Published: (2019-03-01)

WIPI proteins: Biological functions and related syndromes
by: Mohammed Almannai, et al.
Published: (2022-09-01)

Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons
by: Andrea KH Stavoe, et al.
Published: (2019-07-01)

Coiled-coil-mediated dimerization of Atg16 is required for binding to the PROPPIN Atg21
by: Miranda Bueno-Arribas, et al.
Published: (2023-11-01)

A novel autophagy inhibitor, bTBT, disturbs autophagosome formation
by: Momoka Chiba, et al.
Published: (2023-12-01)

WIPI2 enhances the vulnerability of colorectal cancer cells to erastin via bioinformatics analysis and experimental verification
by: Liying Yu, et al.
Published: (2023-05-01)

Systemic Expression Analysis Reveals Prognostic Significance of WIPI3 in Hepatocellular Carcinoma
by: Tao-tao Liang, et al.
Published: (2020-08-01)

CERS6‐AS1 promotes cell proliferation and represses cell apoptosis in pancreatic cancer via miR‐195‐5p/WIPI2 axis
by: Kan‐Fei Gao, et al.
Published: (2022-06-01)

Autophagy receptor optineurin promotes autophagosome formation by potentiating LC3-II production and phagophore maturation
by: Megha Bansal, et al.
Published: (2018-03-01)

Effect of digital wireless technology on the language development of children with cochlear implants
by: Eman Ghorab, et al.
Published: (2018-01-01)

Lymphoid Stress Surveillance Response Contributes to Vitiligo Pathogenesis
by: Liisi Raam, et al.
Published: (2018-11-01)

Whole-Exome Sequencing Identifies Damaging de novo Variants in Anencephalic Cases
by: Linlin Wang, et al.
Published: (2019-11-01)

Comprehensive Analysis of Autophagy-Related Genes in Sweet Orange (<i>Citrus sinensis</i>) Highlights Their Roles in Response to Abiotic Stresses
by: Xing-Zheng Fu, et al.
Published: (2020-04-01)

WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy.
by: Proikas-Cezanne, T, et al.
Published: (2004)

Autophagy and longevity: Evolutionary hints from hyper-longevous mammals
by: Andrea G. Locatelli, et al.
Published: (2022-12-01)

Arbutin increases Caenorhabditis elegans longevity and stress resistance
by: Lin Zhou, et al.
Published: (2017-12-01)

The incredible ULKs
by: Alers Sebastian, et al.
Published: (2012-03-01)

LGG-1/GABARAP lipidation is not required for autophagy and development in Caenorhabditis elegans
by: Romane Leboutet, et al.
Published: (2023-07-01)

Maximizing Longevity and Healthspan: Multiple Approaches All Converging on Autophagy
by: Akshay Bareja, et al.
Published: (2019-09-01)

Atg1 kinase in fission yeast is activated by Atg11-mediated dimerization and cis-autophosphorylation
by: Zhao-Qian Pan, et al.
Published: (2020-09-01)

Neuroendocrine regulation of fat metabolism by autophagy gene atg‐18 in C. elegans dauer larvae
by: Ray Jia, et al.
Published: (2019-09-01)

Autophagy: one more Nobel Prize for yeast
by: Andreas Zimmermann, et al.
Published: (2016-12-01)

Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion
by: Annamaria Mancini, et al.
Published: (2019-02-01)

Progranulin regulation of autophagy contributes to its chondroprotective effect in osteoarthritis
by: Yiming Pan, et al.
Published: (2023-07-01)

Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase
by: Ana Mesquita, et al.
Published: (2015-01-01)

Autophagy Deficiency by Atg4B Loss Leads to Metabolomic Alterations in Mice
by: Gemma G. Martínez-García, et al.
Published: (2021-07-01)

Atg12–Atg3 Coordinates Basal Autophagy, Endolysosomal Trafficking, and Exosome Release
by: Lyndsay Murrow, et al.
Published: (2018-09-01)

Polymorphisms in autophagy genes are genetic susceptibility factors in glioblastoma development
by: E. Bueno-Martínez, et al.
Published: (2022-02-01)

Editorial: Molecular Perspectives for Plant Autophagy Regulation
by: Yan Bao, et al.
Published: (2022-07-01)

TRAF6 regulates autophagy and apoptosis of melanoma cells through c‐Jun/ATG16L2 signaling pathway
by: Yeye Guo, et al.
Published: (2023-08-01)

The Secrets of Alternative Autophagy
by: Kaja Urbańska, et al.
Published: (2021-11-01)

Disrupted autophagy and neuronal dysfunction in C. elegans knockin models of FUS amyotrophic lateral sclerosis
by: Saba N. Baskoylu, et al.
Published: (2022-01-01)

The Association Between Regular Physical Exercise, Sleep Patterns, Fasting, and Autophagy for Healthy Longevity and Well-Being: A Narrative Review
by: Sicheng Min, et al.
Published: (2021-12-01)

HSF-1: Guardian of the Proteome Through Integration of Longevity Signals to the Proteostatic Network
by: Maria I. Lazaro-Pena, et al.
Published: (2022-07-01)

epg5 knockout leads to the impairment of reproductive success and courtship behaviour in a zebrafish model of autophagy-related diseases
by: Camilla M. Fontana, et al.
Published: (2022-04-01)

Identification of AaAtg8 as a marker of autophagy and a functional autophagy-related protein in Aedes albopictus
by: Jialu Qiao, et al.
Published: (2018-11-01)

Conserved Autophagy Pathway Contributes to Stress Tolerance and Virulence and Differentially Controls Autophagic Flux Upon Nutrient Starvation in Cryptococcus neoformans
by: Xueru Zhao, et al.
Published: (2019-11-01)

Pleiotropic Effects of mTOR and Autophagy During Development and Aging
by: Kathrin Schmeisser, et al.
Published: (2019-09-01)

Transcription factors RhPIF4/8 and RhHY5 regulate autophagy-mediated petal senescence in rose (Rosa hybrida)
by: Wenran Wang, et al.
Published: (2023-12-01)

Dephosphorylation of the Atg1 kinase complex by type 2C protein phosphatases
by: Gonen Memisoglu, et al.
Published: (2019-05-01)