A fractional-order mathematical model for examining the spatiotemporal spread of COVID-19 in the presence of vaccine distribution

The spatiotemporal spread of COVID-19 has had a great impact on understanding and addressing the global pandemic. Through analysis of the geographical distribution and temporal patterns of the virus, the hotspot of the virus can be easily detected, giving insights into where intervention is most nee...

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Main Authors: Adedapo Ismaila Alaje, Morufu Oyedunsi Olayiwola
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Healthcare Analytics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772442523000977
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author Adedapo Ismaila Alaje
Morufu Oyedunsi Olayiwola
author_facet Adedapo Ismaila Alaje
Morufu Oyedunsi Olayiwola
author_sort Adedapo Ismaila Alaje
collection DOAJ
description The spatiotemporal spread of COVID-19 has had a great impact on understanding and addressing the global pandemic. Through analysis of the geographical distribution and temporal patterns of the virus, the hotspot of the virus can be easily detected, giving insights into where intervention is most needed. In this study, an efficient method is presented for solving a fractional-order diffusive epidemic model of COVID-19 that incorporates vaccination and is applied to study the spatiotemporal spread of the disease. The method’s convergence is discussed, and the results are found to be applicable and efficient for numerical simulations. The proposed mathematical model is analyzed for its positivity, existence, and uniqueness of solution to demonstrate its feasibility to study physical problems, and a series of numerical simulations are conducted to analyze the spatiotemporal dynamics of COVID-19 in response to vaccine uptake and distribution modeled using the Caputo fractional order derivative. The impact of vaccine uptake and distribution is extensively discussed, and conclusions are drawn.
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spelling doaj.art-ab26fa7d4b5040e38e909af65d33acf72023-07-28T04:27:00ZengElsevierHealthcare Analytics2772-44252023-12-014100230A fractional-order mathematical model for examining the spatiotemporal spread of COVID-19 in the presence of vaccine distributionAdedapo Ismaila Alaje0Morufu Oyedunsi Olayiwola1Department of Mathematical Sciences, Osun State University, Osogbo, NigeriaCorresponding author.; Department of Mathematical Sciences, Osun State University, Osogbo, NigeriaThe spatiotemporal spread of COVID-19 has had a great impact on understanding and addressing the global pandemic. Through analysis of the geographical distribution and temporal patterns of the virus, the hotspot of the virus can be easily detected, giving insights into where intervention is most needed. In this study, an efficient method is presented for solving a fractional-order diffusive epidemic model of COVID-19 that incorporates vaccination and is applied to study the spatiotemporal spread of the disease. The method’s convergence is discussed, and the results are found to be applicable and efficient for numerical simulations. The proposed mathematical model is analyzed for its positivity, existence, and uniqueness of solution to demonstrate its feasibility to study physical problems, and a series of numerical simulations are conducted to analyze the spatiotemporal dynamics of COVID-19 in response to vaccine uptake and distribution modeled using the Caputo fractional order derivative. The impact of vaccine uptake and distribution is extensively discussed, and conclusions are drawn.http://www.sciencedirect.com/science/article/pii/S2772442523000977Fractional-order mathematical modelSimulationModified homotopy perturbation methodDiffusive epidemic modelCOVID-19Vaccination
spellingShingle Adedapo Ismaila Alaje
Morufu Oyedunsi Olayiwola
A fractional-order mathematical model for examining the spatiotemporal spread of COVID-19 in the presence of vaccine distribution
Healthcare Analytics
Fractional-order mathematical model
Simulation
Modified homotopy perturbation method
Diffusive epidemic model
COVID-19
Vaccination
title A fractional-order mathematical model for examining the spatiotemporal spread of COVID-19 in the presence of vaccine distribution
title_full A fractional-order mathematical model for examining the spatiotemporal spread of COVID-19 in the presence of vaccine distribution
title_fullStr A fractional-order mathematical model for examining the spatiotemporal spread of COVID-19 in the presence of vaccine distribution
title_full_unstemmed A fractional-order mathematical model for examining the spatiotemporal spread of COVID-19 in the presence of vaccine distribution
title_short A fractional-order mathematical model for examining the spatiotemporal spread of COVID-19 in the presence of vaccine distribution
title_sort fractional order mathematical model for examining the spatiotemporal spread of covid 19 in the presence of vaccine distribution
topic Fractional-order mathematical model
Simulation
Modified homotopy perturbation method
Diffusive epidemic model
COVID-19
Vaccination
url http://www.sciencedirect.com/science/article/pii/S2772442523000977
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