Jun N-Terminal Kinase 1 Mediates Transcriptional Induction of Matrix Metal loproteinase 9 Expression

Jun N-Terminal Kinase 1 Mediates Transcriptional Induction of Matrix Metal loproteinase 9 Expression

Tumor cell invasion and metastasis require precise coordination of adherence to extracellular matrix (ECM) and controlled degradation of its components. Invasive cells secrete proteolytic enzymes known as matrix metal lop roteinases (MMPs) which degrade specific basement membrane molecules. Expressi...

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Bibliographic Details
Main Authors: David L. Crowe, Kenneth J. Tsang, Babak Shemirani
Format: Article
Language:English
Published: Elsevier 2001-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
invasion
kinase
AP-1
transcription
signal transduction
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558601800130

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http://www.sciencedirect.com/science/article/pii/S1476558601800130

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