The impact of the COVID-19 pandemic on the trend of prescribing long-acting injections of paliperidone and risperidone in Central Serbia
Since the end of 2019, the global spread of COVID-19 has represented a historic event that changed our way of treating patients globally. The use of long-acting injections (LAI) antipsychotics was emphasized. Our goal was to investigate the impact of COVID-19 on the frequency of prescribing LAI and...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-12-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1301835/full |
| _version_ | 1797384233420849152 |
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| author | Milena Stojkovic Marija Sekulic Mirjana Jovanovic Aleksandar Kocovic Danijela Djokovic Natasa Minic Milan Djordjic Stefan Joksimovic Marija Sorak Bojan Stojanovic Snezana Sretenovic Aleksandra Cvetkovic Tamara Stojanovic Olivera Radmanovic Branimir Radmanovic |
| author_facet | Milena Stojkovic Marija Sekulic Mirjana Jovanovic Aleksandar Kocovic Danijela Djokovic Natasa Minic Milan Djordjic Stefan Joksimovic Marija Sorak Bojan Stojanovic Snezana Sretenovic Aleksandra Cvetkovic Tamara Stojanovic Olivera Radmanovic Branimir Radmanovic |
| author_sort | Milena Stojkovic |
| collection | DOAJ |
| description | Since the end of 2019, the global spread of COVID-19 has represented a historic event that changed our way of treating patients globally. The use of long-acting injections (LAI) antipsychotics was emphasized. Our goal was to investigate the impact of COVID-19 on the frequency of prescribing LAI and compare it with a period before. All patients (198) who started LAI-risperidone or LAI-paliperidone for the period 2017–2022, in Kragujevac, the city in Central Serbia, were considered. The frequency of prescribing LAI before and during COVID-19 and the total number of prescribed LAI per year were compared. Separately, the frequency of prescribing LAI-R and the frequency of prescribing LAI-P were compared. The significant (p < 0,05) increase in the use of LAI risperidone and paliperidone was in 2020 and 2021 [per year 2017(3), 2018(6), 2019(26), 2020(75), 2021(55), and 2022(33)]. The significant (p < 0,05) increase in monthly and quarterly preparations of LAI paliperidone was in 2020 and 2021 relative to the years before the pandemic. As the pandemic weakened, the inclusion of LAI paliperidone therapy weakened during 2022. A significant increase in usage of LAI risperidone was in 2022, and in 2020 and 2021 was as it was in the period 2017–2019. During COVID-19, especially in years when COVID-19 restriction measures were stricter, there was a significant change in the application method of antipsychotic therapy in favor of LAI. Regardless of the increase in treatment costs, patients’ interests and protection were prioritized in the treatment process. |
| first_indexed | 2024-03-08T21:32:27Z |
| format | Article |
| id | doaj.art-ab2a9a39782b45bf85b749e0b032c09c |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-03-08T21:32:27Z |
| publishDate | 2023-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-ab2a9a39782b45bf85b749e0b032c09c2023-12-21T04:51:42ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-12-011410.3389/fpsyt.2023.13018351301835The impact of the COVID-19 pandemic on the trend of prescribing long-acting injections of paliperidone and risperidone in Central SerbiaMilena Stojkovic0Marija Sekulic1Mirjana Jovanovic2Aleksandar Kocovic3Danijela Djokovic4Natasa Minic5Milan Djordjic6Stefan Joksimovic7Marija Sorak8Bojan Stojanovic9Snezana Sretenovic10Aleksandra Cvetkovic11Tamara Stojanovic12Olivera Radmanovic13Branimir Radmanovic14Department of Psychiatry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaDepartment of Hygiene and Ecology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaDepartment of Psychiatry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaDepartment of Psychiatry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaDepartment of Psychiatry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaDepartment of Communication Skills, Ethics, and Psychology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaSurgical Oncology Clinic, Institute for Oncology and Radiology of Serbia, Belgrade, SerbiaDepartment of Gynecology and Obstetrics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaDepartment of Surgery, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaDepartment of Ophthalmology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia0Department of Philology and General Education Subjects, Faculty of Philology and Arts in Kragujevac, University of Kragujevac, Kragujevac, Serbia1Internal Clinic, University Clinical Center Kragujevac, Kragujevac, SerbiaDepartment of Psychiatry, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaSince the end of 2019, the global spread of COVID-19 has represented a historic event that changed our way of treating patients globally. The use of long-acting injections (LAI) antipsychotics was emphasized. Our goal was to investigate the impact of COVID-19 on the frequency of prescribing LAI and compare it with a period before. All patients (198) who started LAI-risperidone or LAI-paliperidone for the period 2017–2022, in Kragujevac, the city in Central Serbia, were considered. The frequency of prescribing LAI before and during COVID-19 and the total number of prescribed LAI per year were compared. Separately, the frequency of prescribing LAI-R and the frequency of prescribing LAI-P were compared. The significant (p < 0,05) increase in the use of LAI risperidone and paliperidone was in 2020 and 2021 [per year 2017(3), 2018(6), 2019(26), 2020(75), 2021(55), and 2022(33)]. The significant (p < 0,05) increase in monthly and quarterly preparations of LAI paliperidone was in 2020 and 2021 relative to the years before the pandemic. As the pandemic weakened, the inclusion of LAI paliperidone therapy weakened during 2022. A significant increase in usage of LAI risperidone was in 2022, and in 2020 and 2021 was as it was in the period 2017–2019. During COVID-19, especially in years when COVID-19 restriction measures were stricter, there was a significant change in the application method of antipsychotic therapy in favor of LAI. Regardless of the increase in treatment costs, patients’ interests and protection were prioritized in the treatment process.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1301835/fullCOVID-19 pandemicLAI risperidoneLAI paliperidonemental healthpsychotic disorders |
| spellingShingle | Milena Stojkovic Marija Sekulic Mirjana Jovanovic Aleksandar Kocovic Danijela Djokovic Natasa Minic Milan Djordjic Stefan Joksimovic Marija Sorak Bojan Stojanovic Snezana Sretenovic Aleksandra Cvetkovic Tamara Stojanovic Olivera Radmanovic Branimir Radmanovic The impact of the COVID-19 pandemic on the trend of prescribing long-acting injections of paliperidone and risperidone in Central Serbia Frontiers in Psychiatry COVID-19 pandemic LAI risperidone LAI paliperidone mental health psychotic disorders |
| title | The impact of the COVID-19 pandemic on the trend of prescribing long-acting injections of paliperidone and risperidone in Central Serbia |
| title_full | The impact of the COVID-19 pandemic on the trend of prescribing long-acting injections of paliperidone and risperidone in Central Serbia |
| title_fullStr | The impact of the COVID-19 pandemic on the trend of prescribing long-acting injections of paliperidone and risperidone in Central Serbia |
| title_full_unstemmed | The impact of the COVID-19 pandemic on the trend of prescribing long-acting injections of paliperidone and risperidone in Central Serbia |
| title_short | The impact of the COVID-19 pandemic on the trend of prescribing long-acting injections of paliperidone and risperidone in Central Serbia |
| title_sort | impact of the covid 19 pandemic on the trend of prescribing long acting injections of paliperidone and risperidone in central serbia |
| topic | COVID-19 pandemic LAI risperidone LAI paliperidone mental health psychotic disorders |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1301835/full |
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