Polymorphic variation of mononucleotide microsatellites in healthy humans and its implication for microsatellite instability screening Variação polimórfica de microssatélites mononucleotídicos em indivíduos normais e sua implicação no rastreamento de instabilidade de microssatélites

BACKGROUND: Colorectal cancer is the sixth most common tumor and the fifth in mortality in Brazil. Molecular markers have been associated with disease prognosis, especially in relation to therapeutic response and overall survival rates. Among these, microsatellite instability has been extensively st...

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Bibliographic Details
Main Authors: Silvia Liliana Cossio, Renata dos Santos Coura, Maria Cátira Bortolini, Roberto Giugliani, Patricia Ashton-Prolla, João Carlos Prolla
Format: Article
Language:English
Published: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) 2007-03-01
Series:Arquivos de Gastroenterologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032007000100014