Neuroprotective effects of donepezil against Aβ25-35-induced neurotoxicity

Neuroprotective effects of donepezil against Aβ25-35-induced neurotoxicity

Abstract Purpose The purpose of this study was to investigate the neuroprotective effect of donepezil against β-amyloid25-35 (Aβ25-35)-induced neurotoxicity and the possible mechanism. Methods PC12 cells were conventionally cultured. Serial concentrations of Aβ25-35 and donepezil (0, 0.5, 1, 5, 10,...

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Bibliographic Details
Main Authors:	Bu-Lang Gao, Ning-Ning Che, Xue Li, Chun-Feng Ren
Format:	Article
Language:	English
Published:	BMC 2022-10-01
Series:	European Journal of Medical Research
Subjects:	Donepezil Beta amyloid 25–35 Alzheimer’s disease Protein kinase C Neuroprotection
Online Access:	https://doi.org/10.1186/s40001-022-00862-1

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