Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice.
Alterations in lipid metabolism have been found in several neurodegenerative disorders, including Alzheimer's disease. Lipoprotein lipase (LPL) hydrolyzes triacylglycerides in lipoproteins and regulates lipid metabolism in multiple organs and tissues, including the central nervous system (CNS)....
Main Authors: | Tian Yu, Matthew D Taussig, Nicholas V DiPatrizio, Giuseppe Astarita, Daniele Piomelli, Bryan C Bergman, Mark L Dell'Acqua, Robert H Eckel, Hong Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4532501?pdf=render |
Similar Items
-
Sex differences in obesity development in pair-fed neuronal lipoprotein lipase deficient mice
by: Hong Wang, et al.
Published: (2016-10-01) -
Relationship of decreased hepatic lipase activity and lipoprotein abnormalities to essential fatty acid deficiency in cystic fibrosis patients.
by: E Lévy, et al.
Published: (1989-08-01) -
Distribution and source of lipoprotein lipase in mouse mammary gland
by: DR Jensen, et al.
Published: (1991-05-01) -
Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages
by: Guosong Qiu, et al.
Published: (2007-10-01) -
Lipoprotein lipase and hepatic lipase
by: Marian C. Cheung, et al.
Published: (2003-08-01)