Emergency Endoscopic Interventions in Acute Upper Gastrointestinal Bleeding: A Cohort Study
Introduction: Acute upper gastrointestinal bleeding is a common cause of emergency department admissions. The standard approach for the diagnosis and treatment of acute upper gastrointestinal bleeding (AUGIB) involves an endoscopy of the upper gastrointestinal tract. While daytime emergency endoscop...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/23/3584 |
| _version_ | 1797400338135777280 |
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| author | Anna Mackiewicz-Pracka Piotr Nehring Adam Przybyłkowski |
| author_facet | Anna Mackiewicz-Pracka Piotr Nehring Adam Przybyłkowski |
| author_sort | Anna Mackiewicz-Pracka |
| collection | DOAJ |
| description | Introduction: Acute upper gastrointestinal bleeding is a common cause of emergency department admissions. The standard approach for the diagnosis and treatment of acute upper gastrointestinal bleeding (AUGIB) involves an endoscopy of the upper gastrointestinal tract. While daytime emergency endoscopy has been well studied, there is limited evidence regarding its effectiveness during the nighttime. Patients and Methods: We conducted a retrospective cohort study at a single center, analyzing adult patients with AUGIB referred for emergency endoscopy outside of regular hospital hours. Patients treated with endoscopic hemostatic methods were categorized into day-hours and night-hours groups based on the timing of the gastroscopy. The primary clinical endpoint was 120-day all-cause mortality, with secondary endpoints including hemostasis and recurrence. Results: In the population of 752 enrolled patients with acute upper gastrointestinal bleeding symptoms, 592 had a gastroscopy during the day hours between 8.00 <i>a.m.</i> and 10.00 <i>p.m.</i>, while 160 had procedures performed at night between 10:00 <i>p.m.</i> and 8:00 <i>a.m.</i> In the day-hours group, the median time from symptom onset to endoscopy was 10 h (IQR 6–15), compared to 6 h (IQR 4–16) in the night-hours group. The gastroscopy duration (time to reach hemostasis during endoscopy) was significantly shorter during the night hours (<i>p</i> < 0.001). In both groups, endoscopic intervention after the sixth hour from symptom onset yielded improved outcomes, while treatment before the fifth hour resulted in poorer outcomes. Although the night-hours group had higher 120-day all-cause mortality, the difference was not statistically significant. Conclusions: Our findings indicate that emergency therapeutic gastroscopy for acute upper gastrointestinal bleeding is similarly effective during both day and night hours, particularly when performed after the sixth hour from symptom onset. |
| first_indexed | 2024-03-09T01:53:09Z |
| format | Article |
| id | doaj.art-ab31e38527154d09bde959e70b5eb5b3 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T01:53:09Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-ab31e38527154d09bde959e70b5eb5b32023-12-08T15:13:37ZengMDPI AGDiagnostics2075-44182023-12-011323358410.3390/diagnostics13233584Emergency Endoscopic Interventions in Acute Upper Gastrointestinal Bleeding: A Cohort StudyAnna Mackiewicz-Pracka0Piotr Nehring1Adam Przybyłkowski2Department of Gastroenterology and Internal Medicine, Medical University of Warsaw, 02-091 Warsaw, PolandDepartment of Gastroenterology and Internal Medicine, Medical University of Warsaw, 02-091 Warsaw, PolandDepartment of Gastroenterology and Internal Medicine, Medical University of Warsaw, 02-091 Warsaw, PolandIntroduction: Acute upper gastrointestinal bleeding is a common cause of emergency department admissions. The standard approach for the diagnosis and treatment of acute upper gastrointestinal bleeding (AUGIB) involves an endoscopy of the upper gastrointestinal tract. While daytime emergency endoscopy has been well studied, there is limited evidence regarding its effectiveness during the nighttime. Patients and Methods: We conducted a retrospective cohort study at a single center, analyzing adult patients with AUGIB referred for emergency endoscopy outside of regular hospital hours. Patients treated with endoscopic hemostatic methods were categorized into day-hours and night-hours groups based on the timing of the gastroscopy. The primary clinical endpoint was 120-day all-cause mortality, with secondary endpoints including hemostasis and recurrence. Results: In the population of 752 enrolled patients with acute upper gastrointestinal bleeding symptoms, 592 had a gastroscopy during the day hours between 8.00 <i>a.m.</i> and 10.00 <i>p.m.</i>, while 160 had procedures performed at night between 10:00 <i>p.m.</i> and 8:00 <i>a.m.</i> In the day-hours group, the median time from symptom onset to endoscopy was 10 h (IQR 6–15), compared to 6 h (IQR 4–16) in the night-hours group. The gastroscopy duration (time to reach hemostasis during endoscopy) was significantly shorter during the night hours (<i>p</i> < 0.001). In both groups, endoscopic intervention after the sixth hour from symptom onset yielded improved outcomes, while treatment before the fifth hour resulted in poorer outcomes. Although the night-hours group had higher 120-day all-cause mortality, the difference was not statistically significant. Conclusions: Our findings indicate that emergency therapeutic gastroscopy for acute upper gastrointestinal bleeding is similarly effective during both day and night hours, particularly when performed after the sixth hour from symptom onset.https://www.mdpi.com/2075-4418/13/23/3584acutebleedinggastrointestinalendoscopytherapyupper |
| spellingShingle | Anna Mackiewicz-Pracka Piotr Nehring Adam Przybyłkowski Emergency Endoscopic Interventions in Acute Upper Gastrointestinal Bleeding: A Cohort Study Diagnostics acute bleeding gastrointestinal endoscopy therapy upper |
| title | Emergency Endoscopic Interventions in Acute Upper Gastrointestinal Bleeding: A Cohort Study |
| title_full | Emergency Endoscopic Interventions in Acute Upper Gastrointestinal Bleeding: A Cohort Study |
| title_fullStr | Emergency Endoscopic Interventions in Acute Upper Gastrointestinal Bleeding: A Cohort Study |
| title_full_unstemmed | Emergency Endoscopic Interventions in Acute Upper Gastrointestinal Bleeding: A Cohort Study |
| title_short | Emergency Endoscopic Interventions in Acute Upper Gastrointestinal Bleeding: A Cohort Study |
| title_sort | emergency endoscopic interventions in acute upper gastrointestinal bleeding a cohort study |
| topic | acute bleeding gastrointestinal endoscopy therapy upper |
| url | https://www.mdpi.com/2075-4418/13/23/3584 |
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