GFS, a preparation of Tasmanian <it>Undaria pinnatifida </it>is associated with healing and inhibition of reactivation of Herpes
<p>Abstract</p> <p>Background</p> <p>We sought to assess whether GFS, a proprietary preparation of Tasmanian <it>Undaria pinnatifida</it>, has effects on healing or re-emergence of Herpetic infections, and additionally, to assess effects of GFS <it>in...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2002-11-01
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| Series: | BMC Complementary and Alternative Medicine |
| Online Access: | http://www.biomedcentral.com/1472-6882/2/11 |
| _version_ | 1828229688915394560 |
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| author | Fitton JH Elliot Kate Dragar Charles Cooper Russell Godwin John Thompson Ken |
| author_facet | Fitton JH Elliot Kate Dragar Charles Cooper Russell Godwin John Thompson Ken |
| author_sort | Fitton JH |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>We sought to assess whether GFS, a proprietary preparation of Tasmanian <it>Undaria pinnatifida</it>, has effects on healing or re-emergence of Herpetic infections, and additionally, to assess effects of GFS <it>in vitro</it>. <it>Undaria </it>is the most commonly eaten seaweed in Japan, and contains sulphated polyanions and other components with potential anti-viral activity. Herpes simplex virus type 1 (HSV-1) infections have lower reactivation rates and Herpes type 2 (HSV-2) infections have lower incidence in Japan than in the west.</p> <p>Methods</p> <p>Patients with active (15 subjects) or latent (6 subjects) Herpetic infections (HSV-1, 2, EBV, Zoster) were monitored for response to ingestion of GFS. GFS extract was tested <it>in vitro </it>for human T cell mitogenicity and anti-Herpes activity.</p> <p>Results</p> <p>Ingestion of GFS was associated with increased healing rates in patients with active infections. In addition, patients with latent infection remained asymptomatic whilst ingesting GFS. GFS extract inhibited Herpes viruses <it>in vitro </it>and was mitogenic to human T cells <it>in vitro</it>.</p> <p>Conclusions</p> <p>Ingestion of GFS has inhibitory effects on reactivation and is associated with increased rate of healing after Herpetic outbreaks. GFS extract potently inhibited Herpes virus <it>in vitro</it>, and had mitogenic effects on human T cells.</p> |
| first_indexed | 2024-04-12T18:36:54Z |
| format | Article |
| id | doaj.art-ab3c1b7cbbfb4b75acdc2037523ed87a |
| institution | Directory Open Access Journal |
| issn | 1472-6882 |
| language | English |
| last_indexed | 2024-04-12T18:36:54Z |
| publishDate | 2002-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Complementary and Alternative Medicine |
| spelling | doaj.art-ab3c1b7cbbfb4b75acdc2037523ed87a2022-12-22T03:20:55ZengBMCBMC Complementary and Alternative Medicine1472-68822002-11-01211110.1186/1472-6882-2-11GFS, a preparation of Tasmanian <it>Undaria pinnatifida </it>is associated with healing and inhibition of reactivation of HerpesFitton JHElliot KateDragar CharlesCooper RussellGodwin JohnThompson Ken<p>Abstract</p> <p>Background</p> <p>We sought to assess whether GFS, a proprietary preparation of Tasmanian <it>Undaria pinnatifida</it>, has effects on healing or re-emergence of Herpetic infections, and additionally, to assess effects of GFS <it>in vitro</it>. <it>Undaria </it>is the most commonly eaten seaweed in Japan, and contains sulphated polyanions and other components with potential anti-viral activity. Herpes simplex virus type 1 (HSV-1) infections have lower reactivation rates and Herpes type 2 (HSV-2) infections have lower incidence in Japan than in the west.</p> <p>Methods</p> <p>Patients with active (15 subjects) or latent (6 subjects) Herpetic infections (HSV-1, 2, EBV, Zoster) were monitored for response to ingestion of GFS. GFS extract was tested <it>in vitro </it>for human T cell mitogenicity and anti-Herpes activity.</p> <p>Results</p> <p>Ingestion of GFS was associated with increased healing rates in patients with active infections. In addition, patients with latent infection remained asymptomatic whilst ingesting GFS. GFS extract inhibited Herpes viruses <it>in vitro </it>and was mitogenic to human T cells <it>in vitro</it>.</p> <p>Conclusions</p> <p>Ingestion of GFS has inhibitory effects on reactivation and is associated with increased rate of healing after Herpetic outbreaks. GFS extract potently inhibited Herpes virus <it>in vitro</it>, and had mitogenic effects on human T cells.</p>http://www.biomedcentral.com/1472-6882/2/11 |
| spellingShingle | Fitton JH Elliot Kate Dragar Charles Cooper Russell Godwin John Thompson Ken GFS, a preparation of Tasmanian <it>Undaria pinnatifida </it>is associated with healing and inhibition of reactivation of Herpes BMC Complementary and Alternative Medicine |
| title | GFS, a preparation of Tasmanian <it>Undaria pinnatifida </it>is associated with healing and inhibition of reactivation of Herpes |
| title_full | GFS, a preparation of Tasmanian <it>Undaria pinnatifida </it>is associated with healing and inhibition of reactivation of Herpes |
| title_fullStr | GFS, a preparation of Tasmanian <it>Undaria pinnatifida </it>is associated with healing and inhibition of reactivation of Herpes |
| title_full_unstemmed | GFS, a preparation of Tasmanian <it>Undaria pinnatifida </it>is associated with healing and inhibition of reactivation of Herpes |
| title_short | GFS, a preparation of Tasmanian <it>Undaria pinnatifida </it>is associated with healing and inhibition of reactivation of Herpes |
| title_sort | gfs a preparation of tasmanian it undaria pinnatifida it is associated with healing and inhibition of reactivation of herpes |
| url | http://www.biomedcentral.com/1472-6882/2/11 |
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