Floppy iris syndrome with oral imipramine: A case series
Intraoperative floppy iris syndrome (IFIS) has commonly been seen with long-term use of α1-adrenoceptor blocking agents. We observed IFIS in three patients during phacoemulsification due to oral imipramine therapy. The three patients took imipramine for 25 years, 10 months and 1 year, respectively....
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=2;spage=136;epage=138;aulast=Gupta |
| _version_ | 1798044945450270720 |
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| author | Arvind Gupta Renuka Srinivasan |
| author_facet | Arvind Gupta Renuka Srinivasan |
| author_sort | Arvind Gupta |
| collection | DOAJ |
| description | Intraoperative floppy iris syndrome (IFIS) has commonly been seen with long-term use of α1-adrenoceptor blocking agents. We observed IFIS in three patients during phacoemulsification due to oral imipramine therapy. The three patients took imipramine for 25 years, 10 months and 1 year, respectively. However, only the first patient was on oral therapy at the time of surgery, while the other two patients had stopped 4 months and 2 months prior to undergoing phacoemulsification. The first and third patients developed complete IFIS features, while the second had only partial IFIS characteristics. Phacoemulsification could be completed in all three patients without any complication. None of these patients had history of taking any of the α1-adrenoceptor blocking agents. This is the first anecdotal report of IFIS with the oral use of imipramine and hence further evidences are required to ascertain the association of oral imipramine therapy and IFIS. However, ophthalmologists undertaking phacoemulsification on patients on imipramine therapy should be alert for the occurrence of IFIS. |
| first_indexed | 2024-04-11T23:12:17Z |
| format | Article |
| id | doaj.art-ab3dbd1618824bbc887264ad45ef0337 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-11T23:12:17Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-ab3dbd1618824bbc887264ad45ef03372022-12-22T03:57:46ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892012-01-0160213613810.4103/0301-4738.94057Floppy iris syndrome with oral imipramine: A case seriesArvind GuptaRenuka SrinivasanIntraoperative floppy iris syndrome (IFIS) has commonly been seen with long-term use of α1-adrenoceptor blocking agents. We observed IFIS in three patients during phacoemulsification due to oral imipramine therapy. The three patients took imipramine for 25 years, 10 months and 1 year, respectively. However, only the first patient was on oral therapy at the time of surgery, while the other two patients had stopped 4 months and 2 months prior to undergoing phacoemulsification. The first and third patients developed complete IFIS features, while the second had only partial IFIS characteristics. Phacoemulsification could be completed in all three patients without any complication. None of these patients had history of taking any of the α1-adrenoceptor blocking agents. This is the first anecdotal report of IFIS with the oral use of imipramine and hence further evidences are required to ascertain the association of oral imipramine therapy and IFIS. However, ophthalmologists undertaking phacoemulsification on patients on imipramine therapy should be alert for the occurrence of IFIS.http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=2;spage=136;epage=138;aulast=GuptaOrbitproptosisthyroidHyperhomocysteinemiaretinal arterial occlusionssystemic associationsyoung ageIlluminationletter chartsvisual acuityDacryocystorhinostomyintraocular pressuresystemic effectstimolol maleateAccommodationdynamic retinoscopyophthalmoscopyphotorefractionphotoretinoscopyApoptosiscorneal epitheliumformulationsphingosine-1 phosphateDigital cameraexternal photographphotographyAndroideye handbookiPhonesmart phonetesting toolsAnterior chamber intraocular lensgyrate atrophyposterior dislocation of intraocular lenspsuedophakiaConjunctival ulcerconjunctivitisStenotrophomonas maltophiliaAdrenergic blockerimipramineintraoperative floppy iris syndromeiris hooksphacoemulsification |
| spellingShingle | Arvind Gupta Renuka Srinivasan Floppy iris syndrome with oral imipramine: A case series Indian Journal of Ophthalmology Orbit proptosis thyroid Hyperhomocysteinemia retinal arterial occlusions systemic associations young age Illumination letter charts visual acuity Dacryocystorhinostomy intraocular pressure systemic effects timolol maleate Accommodation dynamic retinoscopy ophthalmoscopy photorefraction photoretinoscopy Apoptosis corneal epithelium formulation sphingosine-1 phosphate Digital camera external photograph photography Android eye handbook iPhone smart phone testing tools Anterior chamber intraocular lens gyrate atrophy posterior dislocation of intraocular lens psuedophakia Conjunctival ulcer conjunctivitis Stenotrophomonas maltophilia Adrenergic blocker imipramine intraoperative floppy iris syndrome iris hooks phacoemulsification |
| title | Floppy iris syndrome with oral imipramine: A case series |
| title_full | Floppy iris syndrome with oral imipramine: A case series |
| title_fullStr | Floppy iris syndrome with oral imipramine: A case series |
| title_full_unstemmed | Floppy iris syndrome with oral imipramine: A case series |
| title_short | Floppy iris syndrome with oral imipramine: A case series |
| title_sort | floppy iris syndrome with oral imipramine a case series |
| topic | Orbit proptosis thyroid Hyperhomocysteinemia retinal arterial occlusions systemic associations young age Illumination letter charts visual acuity Dacryocystorhinostomy intraocular pressure systemic effects timolol maleate Accommodation dynamic retinoscopy ophthalmoscopy photorefraction photoretinoscopy Apoptosis corneal epithelium formulation sphingosine-1 phosphate Digital camera external photograph photography Android eye handbook iPhone smart phone testing tools Anterior chamber intraocular lens gyrate atrophy posterior dislocation of intraocular lens psuedophakia Conjunctival ulcer conjunctivitis Stenotrophomonas maltophilia Adrenergic blocker imipramine intraoperative floppy iris syndrome iris hooks phacoemulsification |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=2;spage=136;epage=138;aulast=Gupta |
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