Inhibition of Ca<sup>2+</sup>/Calmodulin-dependent protein kinase II reverses oxaliplatin-induced mechanical allodynia in Rats
<p>Abstract</p> <p>Background</p> <p>Oxaliplatin is a key drug in the treatment of colorectal cancer, but it causes severe peripheral neuropathy. We previously reported that oxaliplatin (4 mg/kg, i.p., twice a week) induces mechanical allodynia in the late phase in rats...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2012-04-01
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| Series: | Molecular Pain |
| Online Access: | http://www.molecularpain.com/content/8/1/26 |