Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma
Abstract Background Exercise is widely known to lower intraocular pressure and increase ocular blood flow, which may be beneficial for glaucoma management. However, there are few studies that have reported on the relationship between exercise and glaucoma progression. The aim of our study was to inv...
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| Format: | Article |
| Language: | English |
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BMC
2020-03-01
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| Series: | Eye and Vision |
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| Online Access: | http://link.springer.com/article/10.1186/s40662-020-0175-9 |
| _version_ | 1818992717773930496 |
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| author | Xiafei Pan Kai Xu Xin Wang Guofu Chen Huanhuan Cheng Alice Jia Liu Laurence Tang Hou Lin Zhong Jie Chen Yuanbo Liang |
| author_facet | Xiafei Pan Kai Xu Xin Wang Guofu Chen Huanhuan Cheng Alice Jia Liu Laurence Tang Hou Lin Zhong Jie Chen Yuanbo Liang |
| author_sort | Xiafei Pan |
| collection | DOAJ |
| description | Abstract Background Exercise is widely known to lower intraocular pressure and increase ocular blood flow, which may be beneficial for glaucoma management. However, there are few studies that have reported on the relationship between exercise and glaucoma progression. The aim of our study was to investigate the exercise habits of those with primary open angle glaucoma (POAG) and its association with the progression of visual field (VF) loss. Methods Daily physical activity (PA) was monitored by an accelerometer (ActiGraph wGT3x-BT) which patients wore for more than 10 h of being awake on their right wrists for 1 week. Results Seventy-one non-progressive and 27 progressive patients were enrolled in the study. 24-h moderate to vigorous physical activity (MVPA) exercise showed that POAG patients had similar variation trends consisting of 3 wave peaks and 2 wave hollows. Minutes spent in MVPA was 19.89 ± 15.81 and 21.62 ± 15.10 during 07:00–09:00 h (p = 0.204), 15.40 ± 14.49 and 15.67 ± 12.43 during 15:00–17:00 h (p = 0.822) and 17.26 ± 21.11 and 11.42 ± 11.58 during 18:00–20:00 h (p = 0.001) in the non-progressive and progressive group, respectively. Univariate analysis indicated that 10 min of MVPA (18:00–20:00 h) [odds ratio, OR (95% CI) = 0.82 (0.73, 0.92)], average mean arterial pressure [OR (95% CI) = 0.96 (0.94, 0.98)], age [OR (95% CI) = 1.06 (1.03, 1.08)], male [OR (95% CI) = 0.67 (0.48, 0.96)], spherical equivalent [OR (95% CI) = 1.14 (1.07, 1.22)] and IOP-lowering medications [OR (95% CI) = 1.54 (1.16, 2.05)] were significantly correlated with having progressive VF damage. Multivariable analysis showed that 10 min of MVPA (18:00–20:00 h) [OR (95% CI) = 0.85 (0.75, 0.97)] was associated with progressive VF loss even after adjusting for other risk factors. Conclusions Evening exercise may lower the odds of VF progression, suggesting that exercise habits possibly play an important role in glaucoma progression. |
| first_indexed | 2024-12-20T20:30:36Z |
| format | Article |
| id | doaj.art-ab41cdc4426c4979bdb56d840e99df8e |
| institution | Directory Open Access Journal |
| issn | 2326-0254 |
| language | English |
| last_indexed | 2024-12-20T20:30:36Z |
| publishDate | 2020-03-01 |
| publisher | BMC |
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| series | Eye and Vision |
| spelling | doaj.art-ab41cdc4426c4979bdb56d840e99df8e2022-12-21T19:27:22ZengBMCEye and Vision2326-02542020-03-01711810.1186/s40662-020-0175-9Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucomaXiafei Pan0Kai Xu1Xin Wang2Guofu Chen3Huanhuan Cheng4Alice Jia Liu5Laurence Tang Hou6Lin Zhong7Jie Chen8Yuanbo Liang9Department of Ophthalmology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen UniversityNanjing Sport InstituteSchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical UniversitySchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical UniversitySchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical UniversitySchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical UniversityJohns Hopkins University School of MedicineSchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical UniversitySchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical UniversitySchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical UniversityAbstract Background Exercise is widely known to lower intraocular pressure and increase ocular blood flow, which may be beneficial for glaucoma management. However, there are few studies that have reported on the relationship between exercise and glaucoma progression. The aim of our study was to investigate the exercise habits of those with primary open angle glaucoma (POAG) and its association with the progression of visual field (VF) loss. Methods Daily physical activity (PA) was monitored by an accelerometer (ActiGraph wGT3x-BT) which patients wore for more than 10 h of being awake on their right wrists for 1 week. Results Seventy-one non-progressive and 27 progressive patients were enrolled in the study. 24-h moderate to vigorous physical activity (MVPA) exercise showed that POAG patients had similar variation trends consisting of 3 wave peaks and 2 wave hollows. Minutes spent in MVPA was 19.89 ± 15.81 and 21.62 ± 15.10 during 07:00–09:00 h (p = 0.204), 15.40 ± 14.49 and 15.67 ± 12.43 during 15:00–17:00 h (p = 0.822) and 17.26 ± 21.11 and 11.42 ± 11.58 during 18:00–20:00 h (p = 0.001) in the non-progressive and progressive group, respectively. Univariate analysis indicated that 10 min of MVPA (18:00–20:00 h) [odds ratio, OR (95% CI) = 0.82 (0.73, 0.92)], average mean arterial pressure [OR (95% CI) = 0.96 (0.94, 0.98)], age [OR (95% CI) = 1.06 (1.03, 1.08)], male [OR (95% CI) = 0.67 (0.48, 0.96)], spherical equivalent [OR (95% CI) = 1.14 (1.07, 1.22)] and IOP-lowering medications [OR (95% CI) = 1.54 (1.16, 2.05)] were significantly correlated with having progressive VF damage. Multivariable analysis showed that 10 min of MVPA (18:00–20:00 h) [OR (95% CI) = 0.85 (0.75, 0.97)] was associated with progressive VF loss even after adjusting for other risk factors. Conclusions Evening exercise may lower the odds of VF progression, suggesting that exercise habits possibly play an important role in glaucoma progression.http://link.springer.com/article/10.1186/s40662-020-0175-9GlaucomaExercise habitsVisual field progression |
| spellingShingle | Xiafei Pan Kai Xu Xin Wang Guofu Chen Huanhuan Cheng Alice Jia Liu Laurence Tang Hou Lin Zhong Jie Chen Yuanbo Liang Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma Eye and Vision Glaucoma Exercise habits Visual field progression |
| title | Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma |
| title_full | Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma |
| title_fullStr | Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma |
| title_full_unstemmed | Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma |
| title_short | Evening exercise is associated with lower odds of visual field progression in Chinese patients with primary open angle glaucoma |
| title_sort | evening exercise is associated with lower odds of visual field progression in chinese patients with primary open angle glaucoma |
| topic | Glaucoma Exercise habits Visual field progression |
| url | http://link.springer.com/article/10.1186/s40662-020-0175-9 |
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