VITAMIN D STATUS IN COVID-19 PATIENTS ADMITTED TO THE CRITICAL CARE UNIT OFAN EASTERN INDIA HOSPITAL
The COVID-19 patients experienced acute respiratory distress during their SARS-CoV-2 infections. The present observational study was undertaken to find out the possible association between vitamin D and COVID-19 clinical severity in a tertiary care hospital from November 2021 to February 2022. Pat...
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| Format: | Article |
| Language: | English |
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West Bengal Veterinary Alumni Association
2023-06-01
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| Series: | Exploratory Animal and Medical Research |
| Subjects: | |
| Online Access: | https://www.animalmedicalresearch.org/Vol.13_Issue-1_June_2023/VITAMIN%20D%20STATUS%20IN%20COVID-19.pdf |
| _version_ | 1797776611969335296 |
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| author | Avijit Saha Sangeeta Ghosh Sandip Ghosh Sanjay Vashistha Tapas Kumar Sur |
| author_facet | Avijit Saha Sangeeta Ghosh Sandip Ghosh Sanjay Vashistha Tapas Kumar Sur |
| author_sort | Avijit Saha |
| collection | DOAJ |
| description | The COVID-19 patients experienced acute respiratory distress during their SARS-CoV-2 infections. The present
observational study was undertaken to find out the possible association between vitamin D and COVID-19 clinical severity in a
tertiary care hospital from November 2021 to February 2022. Patients admitted to the hospital’s Critical Care Unit (CCU) with
SARS-CoV-2 illness were selected for blood vitamin D estimations. Patients’ conditions were evaluated clinically and correlated
with serum vitamin D levels. Out of a total of 97 COVID-19 patients selected, 64.9% were male. Clinically, 41.3% of patients
had a severe COVID-19 infection, compared to a moderate infection incidence of 58.7%. Among them, 19.6% and 42.2% were
found to be vitamin D deficient and vitamin D insufficient, respectively. Serum vitamin D was significantly (p<0.001) reduced
with age (≤ 60 yrs vs. ≥ 60 yrs) and with disease severe (moderate vs. severe). The insufficiency/deficiency of vitamin D was
higher among the aged acute respiratory-infected COVID-19 patients. Therefore, vitamin D deficiency may be one of the main
causes of severe illness in SARS-CoV-2 patients. |
| first_indexed | 2024-03-12T22:53:17Z |
| format | Article |
| id | doaj.art-ab446a962cc74313a0efd30f37ed13e6 |
| institution | Directory Open Access Journal |
| issn | 2277-470X 2319-247X |
| language | English |
| last_indexed | 2024-03-12T22:53:17Z |
| publishDate | 2023-06-01 |
| publisher | West Bengal Veterinary Alumni Association |
| record_format | Article |
| series | Exploratory Animal and Medical Research |
| spelling | doaj.art-ab446a962cc74313a0efd30f37ed13e62023-07-20T06:36:36ZengWest Bengal Veterinary Alumni AssociationExploratory Animal and Medical Research2277-470X2319-247X2023-06-01131162110.52635/eamr/13.1.16-21VITAMIN D STATUS IN COVID-19 PATIENTS ADMITTED TO THE CRITICAL CARE UNIT OFAN EASTERN INDIA HOSPITALAvijit Saha0Sangeeta Ghosh1Sandip Ghosh2Sanjay Vashistha3Tapas Kumar Sur4Department of Biochemistry, R.G. Kar Medical College and Hospital, Kolkata, West Bengal, IndiaDepartment of Microbiology, R.G. Kar Medical College and Hospital, Kolkata, West Bengal, IndiaPrincipal, R.G. Kar Medical College and Hospital, Kolkata, West Bengal, IndiaM.S.V.P. , R.G. Kar Medical College and Hospital, Kolkata, West Bengal, India Multidisciplinary Research Unit, R.G. Kar Medical College and Hospital, Kolkata, West Bengal, IndiaThe COVID-19 patients experienced acute respiratory distress during their SARS-CoV-2 infections. The present observational study was undertaken to find out the possible association between vitamin D and COVID-19 clinical severity in a tertiary care hospital from November 2021 to February 2022. Patients admitted to the hospital’s Critical Care Unit (CCU) with SARS-CoV-2 illness were selected for blood vitamin D estimations. Patients’ conditions were evaluated clinically and correlated with serum vitamin D levels. Out of a total of 97 COVID-19 patients selected, 64.9% were male. Clinically, 41.3% of patients had a severe COVID-19 infection, compared to a moderate infection incidence of 58.7%. Among them, 19.6% and 42.2% were found to be vitamin D deficient and vitamin D insufficient, respectively. Serum vitamin D was significantly (p<0.001) reduced with age (≤ 60 yrs vs. ≥ 60 yrs) and with disease severe (moderate vs. severe). The insufficiency/deficiency of vitamin D was higher among the aged acute respiratory-infected COVID-19 patients. Therefore, vitamin D deficiency may be one of the main causes of severe illness in SARS-CoV-2 patients.https://www.animalmedicalresearch.org/Vol.13_Issue-1_June_2023/VITAMIN%20D%20STATUS%20IN%20COVID-19.pdfcovid-19sars-cov-2vitamin dimmunityacute respiratory distress |
| spellingShingle | Avijit Saha Sangeeta Ghosh Sandip Ghosh Sanjay Vashistha Tapas Kumar Sur VITAMIN D STATUS IN COVID-19 PATIENTS ADMITTED TO THE CRITICAL CARE UNIT OFAN EASTERN INDIA HOSPITAL Exploratory Animal and Medical Research covid-19 sars-cov-2 vitamin d immunity acute respiratory distress |
| title | VITAMIN D STATUS IN COVID-19 PATIENTS ADMITTED TO THE CRITICAL CARE UNIT OFAN EASTERN INDIA HOSPITAL |
| title_full | VITAMIN D STATUS IN COVID-19 PATIENTS ADMITTED TO THE CRITICAL CARE UNIT OFAN EASTERN INDIA HOSPITAL |
| title_fullStr | VITAMIN D STATUS IN COVID-19 PATIENTS ADMITTED TO THE CRITICAL CARE UNIT OFAN EASTERN INDIA HOSPITAL |
| title_full_unstemmed | VITAMIN D STATUS IN COVID-19 PATIENTS ADMITTED TO THE CRITICAL CARE UNIT OFAN EASTERN INDIA HOSPITAL |
| title_short | VITAMIN D STATUS IN COVID-19 PATIENTS ADMITTED TO THE CRITICAL CARE UNIT OFAN EASTERN INDIA HOSPITAL |
| title_sort | vitamin d status in covid 19 patients admitted to the critical care unit ofan eastern india hospital |
| topic | covid-19 sars-cov-2 vitamin d immunity acute respiratory distress |
| url | https://www.animalmedicalresearch.org/Vol.13_Issue-1_June_2023/VITAMIN%20D%20STATUS%20IN%20COVID-19.pdf |
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