Metastatic Extraskeletal Mesenchymal Chondrosarcoma of the Pancreas: Report of an Unusual Case with Review of Literature

Extraskeletal mesenchymal chondrosarcoma (ESMC) metastasizing to the pancreas in isolation is a rare occurrence. We report a 49-year-old gentleman who had undergone excision of an ESMC of the thigh in 2009 and presented with sudden onset abdominal pain and icterus in 2019. Radiological imaging revea...

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Main Authors: Saloni Naresh Shah, Ashok Parameswaran, Prasanna Kumar Reddy
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2021-01-01
Series:Asian Journal of Oncology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1722807
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author Saloni Naresh Shah
Ashok Parameswaran
Prasanna Kumar Reddy
author_facet Saloni Naresh Shah
Ashok Parameswaran
Prasanna Kumar Reddy
author_sort Saloni Naresh Shah
collection DOAJ
description Extraskeletal mesenchymal chondrosarcoma (ESMC) metastasizing to the pancreas in isolation is a rare occurrence. We report a 49-year-old gentleman who had undergone excision of an ESMC of the thigh in 2009 and presented with sudden onset abdominal pain and icterus in 2019. Radiological imaging revealed calcified mass of the pancreas with multiple nodules with extension into the adipose tissue. Distal pancreatectomy was performed and the pathology revealed a bimorphic tumor composed of undifferentiated round blue cells with abrupt transition to hyaline cartilage, typical of mesenchymal chondrosarcoma. To the best of our knowledge, there are only seven prior cases of metastatic ESMC of the pancreas in the English literature. Surgical intervention appears to be the preferred modality of treatment for metastatic pancreatic tumors. These patients may have long latency period before metastasizing and seem to have a good survival period post excision.
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spelling doaj.art-ab4623027fd146b7b4e4e74cbe191a7f2022-12-21T21:30:32ZengThieme Medical Publishers, Inc.Asian Journal of Oncology2454-67982455-46182021-01-01070315215510.1055/s-0040-1722807Metastatic Extraskeletal Mesenchymal Chondrosarcoma of the Pancreas: Report of an Unusual Case with Review of LiteratureSaloni Naresh Shah0Ashok Parameswaran1Prasanna Kumar Reddy2Department of Histopathology and Cytology, Apollo Hospitals, Chennai, Tamil Nadu, IndiaDepartment of Histopathology and Cytology, Apollo Hospitals, Chennai, Tamil Nadu, IndiaDepartment of Surgical Gastroenterology and Minimal Access Surgery, Apollo Main Hospitals, Chennai, Tamil Nadu, IndiaExtraskeletal mesenchymal chondrosarcoma (ESMC) metastasizing to the pancreas in isolation is a rare occurrence. We report a 49-year-old gentleman who had undergone excision of an ESMC of the thigh in 2009 and presented with sudden onset abdominal pain and icterus in 2019. Radiological imaging revealed calcified mass of the pancreas with multiple nodules with extension into the adipose tissue. Distal pancreatectomy was performed and the pathology revealed a bimorphic tumor composed of undifferentiated round blue cells with abrupt transition to hyaline cartilage, typical of mesenchymal chondrosarcoma. To the best of our knowledge, there are only seven prior cases of metastatic ESMC of the pancreas in the English literature. Surgical intervention appears to be the preferred modality of treatment for metastatic pancreatic tumors. These patients may have long latency period before metastasizing and seem to have a good survival period post excision.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1722807extraskeletal mesenchymal chondrosarcomametastasispancreas
spellingShingle Saloni Naresh Shah
Ashok Parameswaran
Prasanna Kumar Reddy
Metastatic Extraskeletal Mesenchymal Chondrosarcoma of the Pancreas: Report of an Unusual Case with Review of Literature
Asian Journal of Oncology
extraskeletal mesenchymal chondrosarcoma
metastasis
pancreas
title Metastatic Extraskeletal Mesenchymal Chondrosarcoma of the Pancreas: Report of an Unusual Case with Review of Literature
title_full Metastatic Extraskeletal Mesenchymal Chondrosarcoma of the Pancreas: Report of an Unusual Case with Review of Literature
title_fullStr Metastatic Extraskeletal Mesenchymal Chondrosarcoma of the Pancreas: Report of an Unusual Case with Review of Literature
title_full_unstemmed Metastatic Extraskeletal Mesenchymal Chondrosarcoma of the Pancreas: Report of an Unusual Case with Review of Literature
title_short Metastatic Extraskeletal Mesenchymal Chondrosarcoma of the Pancreas: Report of an Unusual Case with Review of Literature
title_sort metastatic extraskeletal mesenchymal chondrosarcoma of the pancreas report of an unusual case with review of literature
topic extraskeletal mesenchymal chondrosarcoma
metastasis
pancreas
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1722807
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AT prasannakumarreddy metastaticextraskeletalmesenchymalchondrosarcomaofthepancreasreportofanunusualcasewithreviewofliterature