A review of preoperative chemoradiotherapy for lower rectal cancer
In Western countries, rectal cancer has been treated by chemoradiotherapy (CRT) for several decades now, and good local control has been reported. However, Japanese guidelines did not strongly recommend CRT, because CRT is only useful for achieving local control and imbues no survival benefit. For t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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The Japan Society of Coloproctology
2017-07-01
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| Series: | Journal of the Anus, Rectum and Colon |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jarc/1/3/1_2017-013/_pdf/-char/en |
| _version_ | 1818349886812192768 |
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| author | Naohito Beppu Hidenori Yanagi Naohiro Tomita |
| author_facet | Naohito Beppu Hidenori Yanagi Naohiro Tomita |
| author_sort | Naohito Beppu |
| collection | DOAJ |
| description | In Western countries, rectal cancer has been treated by chemoradiotherapy (CRT) for several decades now, and good local control has been reported. However, Japanese guidelines did not strongly recommend CRT, because CRT is only useful for achieving local control and imbues no survival benefit. For this reason, CRT was rarely used to treat rectal cancer in Japan. However, in the 2000s, several studies involving CRT began to be reported from Western countries, such as “correlation between pathological complete response and survival,” “induction chemotherapy followed by CRT,” and “watch-and-wait policies.” These studies were directly correlated with survival of and benefits to the patients. Given these findings, Japanese institutions have recently begun to introduce CRT for rectal cancer. Therefore, in the present study, we reviewed several topics regarding CRT for rectal cancer. |
| first_indexed | 2024-12-13T18:13:05Z |
| format | Article |
| id | doaj.art-ab49f3aa426f4f638b6ad6a95903636a |
| institution | Directory Open Access Journal |
| issn | 2432-3853 |
| language | English |
| last_indexed | 2024-12-13T18:13:05Z |
| publishDate | 2017-07-01 |
| publisher | The Japan Society of Coloproctology |
| record_format | Article |
| series | Journal of the Anus, Rectum and Colon |
| spelling | doaj.art-ab49f3aa426f4f638b6ad6a95903636a2022-12-21T23:35:55ZengThe Japan Society of ColoproctologyJournal of the Anus, Rectum and Colon2432-38532017-07-0113657310.23922/jarc.2017-0132017-013A review of preoperative chemoradiotherapy for lower rectal cancerNaohito Beppu0Hidenori Yanagi1Naohiro Tomita2Department of Surgery, Meiwa Hospital NishinomiyaDepartment of Surgery, Meiwa Hospital NishinomiyaDivision of Lower Gastrointestinal Surgery, Department of Surgery, Hyogo College of MedicineIn Western countries, rectal cancer has been treated by chemoradiotherapy (CRT) for several decades now, and good local control has been reported. However, Japanese guidelines did not strongly recommend CRT, because CRT is only useful for achieving local control and imbues no survival benefit. For this reason, CRT was rarely used to treat rectal cancer in Japan. However, in the 2000s, several studies involving CRT began to be reported from Western countries, such as “correlation between pathological complete response and survival,” “induction chemotherapy followed by CRT,” and “watch-and-wait policies.” These studies were directly correlated with survival of and benefits to the patients. Given these findings, Japanese institutions have recently begun to introduce CRT for rectal cancer. Therefore, in the present study, we reviewed several topics regarding CRT for rectal cancer.https://www.jstage.jst.go.jp/article/jarc/1/3/1_2017-013/_pdf/-char/enrectal cancerchemoradiotherapyradiosensitizeradjuvant chemotherapylateral lymph node dissection |
| spellingShingle | Naohito Beppu Hidenori Yanagi Naohiro Tomita A review of preoperative chemoradiotherapy for lower rectal cancer Journal of the Anus, Rectum and Colon rectal cancer chemoradiotherapy radiosensitizer adjuvant chemotherapy lateral lymph node dissection |
| title | A review of preoperative chemoradiotherapy for lower rectal cancer |
| title_full | A review of preoperative chemoradiotherapy for lower rectal cancer |
| title_fullStr | A review of preoperative chemoradiotherapy for lower rectal cancer |
| title_full_unstemmed | A review of preoperative chemoradiotherapy for lower rectal cancer |
| title_short | A review of preoperative chemoradiotherapy for lower rectal cancer |
| title_sort | review of preoperative chemoradiotherapy for lower rectal cancer |
| topic | rectal cancer chemoradiotherapy radiosensitizer adjuvant chemotherapy lateral lymph node dissection |
| url | https://www.jstage.jst.go.jp/article/jarc/1/3/1_2017-013/_pdf/-char/en |
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