NPM1 silencing reduces tumour growth and MAPK signalling in prostate cancer cells.
The chaperone nucleophosmin (NPM1) is over-expressed in the epithelial compartment of prostate tumours compared to adjacent healthy epithelium and may represent one of the key actors that support the neoplastic phenotype of prostate adenocarcinoma cells. Yet, the mechanisms that underlie NPM1 mediat...
Main Authors: | Gaëlle Loubeau, Rafik Boudra, Sabrina Maquaire, Corinne Lours-Calet, Claude Beaudoin, Pierre Verrelle, Laurent Morel |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4010470?pdf=render |
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