Short-term side effects of COVID-19 vaccines among healthcare workers: a multicenter study in Iran
Abstract Since the initiation of the COVID-19 vaccination effort, there has been widespread concern regarding vaccine efficacy and potential side effects. This study aimed to explore the short-term side effects of four available COVID-19 vaccines (Sputnik V, Sinopharm, Oxford–AstraZeneca, and Covaxi...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-02-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-54450-w |
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| author | Kayvan Mirnia Elmira Haji Esmaeil Memar Niyoosha Kamran Saadollah Yeganedoost Zeynab Nickhah Klashami Setareh Mamishi Shima Mahmoudi |
| author_facet | Kayvan Mirnia Elmira Haji Esmaeil Memar Niyoosha Kamran Saadollah Yeganedoost Zeynab Nickhah Klashami Setareh Mamishi Shima Mahmoudi |
| author_sort | Kayvan Mirnia |
| collection | DOAJ |
| description | Abstract Since the initiation of the COVID-19 vaccination effort, there has been widespread concern regarding vaccine efficacy and potential side effects. This study aimed to explore the short-term side effects of four available COVID-19 vaccines (Sputnik V, Sinopharm, Oxford–AstraZeneca, and Covaxin) among healthcare workers (HCWs) in Iran. The multicenter study involved 1575 HCWs, with the majority received Sputnik V (74.1%), followed by Covaxin (15.6%), Sinopharm (6.4%), and Oxford-AstraZeneca (3.8%). The prevalence of at least one side effect after the first and second dose COVID-19 vaccine was 84.6% and 72.9%, respectively. The common side effects (presented in > 50% of the study participants) after the first dose of the vaccine were injection site pain (61.7%), myalgia (51.8%), and muscle pain (50.9%). The most reported side effects after the second dose of the vaccine were injection site pain (26.8%), myalgia (15.8%), fever (10.3%), headache (9.9%), and chills (9.2%). In conclusion, according to the COVID-19 vaccine type, different side effects might occur following the first and second doses of vaccination. These findings assist in addressing the ongoing problems of vaccination hesitancy which has been driven by widespread worries about the vaccine safety profile. |
| first_indexed | 2024-03-07T15:05:31Z |
| format | Article |
| id | doaj.art-ab5234a01ea14fe3bad6de5da89fc331 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-07T15:05:31Z |
| publishDate | 2024-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-ab5234a01ea14fe3bad6de5da89fc3312024-03-05T18:55:33ZengNature PortfolioScientific Reports2045-23222024-02-011411710.1038/s41598-024-54450-wShort-term side effects of COVID-19 vaccines among healthcare workers: a multicenter study in IranKayvan Mirnia0Elmira Haji Esmaeil Memar1Niyoosha Kamran2Saadollah Yeganedoost3Zeynab Nickhah Klashami4Setareh Mamishi5Shima Mahmoudi6Department of Neonatology, Pediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical SciencesPediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical SciencesDepartment of Pediatrics, Pediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical SciencesDepartment of Neonatology, Tabriz University of Medical ScienceEndocrinology and Metabolism Research Institute (EMRI), Tehran University of Medical SciencesPediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical SciencesPediatric Infectious Disease Research Center, Pediatrics Center of Excellence, Children’s Medical Center Hospital, Tehran University of Medical SciencesAbstract Since the initiation of the COVID-19 vaccination effort, there has been widespread concern regarding vaccine efficacy and potential side effects. This study aimed to explore the short-term side effects of four available COVID-19 vaccines (Sputnik V, Sinopharm, Oxford–AstraZeneca, and Covaxin) among healthcare workers (HCWs) in Iran. The multicenter study involved 1575 HCWs, with the majority received Sputnik V (74.1%), followed by Covaxin (15.6%), Sinopharm (6.4%), and Oxford-AstraZeneca (3.8%). The prevalence of at least one side effect after the first and second dose COVID-19 vaccine was 84.6% and 72.9%, respectively. The common side effects (presented in > 50% of the study participants) after the first dose of the vaccine were injection site pain (61.7%), myalgia (51.8%), and muscle pain (50.9%). The most reported side effects after the second dose of the vaccine were injection site pain (26.8%), myalgia (15.8%), fever (10.3%), headache (9.9%), and chills (9.2%). In conclusion, according to the COVID-19 vaccine type, different side effects might occur following the first and second doses of vaccination. These findings assist in addressing the ongoing problems of vaccination hesitancy which has been driven by widespread worries about the vaccine safety profile.https://doi.org/10.1038/s41598-024-54450-wCOVID-19Healthcare workersSide effectsVaccineIran |
| spellingShingle | Kayvan Mirnia Elmira Haji Esmaeil Memar Niyoosha Kamran Saadollah Yeganedoost Zeynab Nickhah Klashami Setareh Mamishi Shima Mahmoudi Short-term side effects of COVID-19 vaccines among healthcare workers: a multicenter study in Iran Scientific Reports COVID-19 Healthcare workers Side effects Vaccine Iran |
| title | Short-term side effects of COVID-19 vaccines among healthcare workers: a multicenter study in Iran |
| title_full | Short-term side effects of COVID-19 vaccines among healthcare workers: a multicenter study in Iran |
| title_fullStr | Short-term side effects of COVID-19 vaccines among healthcare workers: a multicenter study in Iran |
| title_full_unstemmed | Short-term side effects of COVID-19 vaccines among healthcare workers: a multicenter study in Iran |
| title_short | Short-term side effects of COVID-19 vaccines among healthcare workers: a multicenter study in Iran |
| title_sort | short term side effects of covid 19 vaccines among healthcare workers a multicenter study in iran |
| topic | COVID-19 Healthcare workers Side effects Vaccine Iran |
| url | https://doi.org/10.1038/s41598-024-54450-w |
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