Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid Leukemia

Posaconazole is a commonly used medication for antifungal prophylaxis in patients with high-risk acute leukemia, such as acute myeloid leukemia. Despite clinical data that show that posaconazole is superior to other antifungal prophylaxis medications, posaconazole is known to have many side effects...

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Main Authors: Mayur D. Mody MD, Deepak Ravindranathan MD, Harpaul S. Gill MD, Vamsi K. Kota MD
Format: Article
Language:English
Published: SAGE Publishing 2017-02-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/2324709617690747
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author Mayur D. Mody MD
Deepak Ravindranathan MD
Harpaul S. Gill MD
Vamsi K. Kota MD
author_facet Mayur D. Mody MD
Deepak Ravindranathan MD
Harpaul S. Gill MD
Vamsi K. Kota MD
author_sort Mayur D. Mody MD
collection DOAJ
description Posaconazole is a commonly used medication for antifungal prophylaxis in patients with high-risk acute leukemia, such as acute myeloid leukemia. Despite clinical data that show that posaconazole is superior to other antifungal prophylaxis medications, posaconazole is known to have many side effects and drug-drug interactions. We present a patient who developed rhabdomyolysis after being started on posaconazole for prophylaxis in the setting of relapsed acute myeloid leukemia.
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spelling doaj.art-ab5600cd5ce3499c92034282a3f1b38c2022-12-22T03:50:29ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962017-02-01510.1177/232470961769074710.1177_2324709617690747Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid LeukemiaMayur D. Mody MD0Deepak Ravindranathan MD1Harpaul S. Gill MD2Vamsi K. Kota MD3Emory University, Atlanta, GA, USAEmory University, Atlanta, GA, USAEmory University, Atlanta, GA, USAEmory University, Atlanta, GA, USAPosaconazole is a commonly used medication for antifungal prophylaxis in patients with high-risk acute leukemia, such as acute myeloid leukemia. Despite clinical data that show that posaconazole is superior to other antifungal prophylaxis medications, posaconazole is known to have many side effects and drug-drug interactions. We present a patient who developed rhabdomyolysis after being started on posaconazole for prophylaxis in the setting of relapsed acute myeloid leukemia.https://doi.org/10.1177/2324709617690747
spellingShingle Mayur D. Mody MD
Deepak Ravindranathan MD
Harpaul S. Gill MD
Vamsi K. Kota MD
Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid Leukemia
Journal of Investigative Medicine High Impact Case Reports
title Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid Leukemia
title_full Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid Leukemia
title_fullStr Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid Leukemia
title_full_unstemmed Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid Leukemia
title_short Rhabdomyolysis Following Initiation of Posaconazole Use for Antifungal Prophylaxis in a Patient With Relapsed Acute Myeloid Leukemia
title_sort rhabdomyolysis following initiation of posaconazole use for antifungal prophylaxis in a patient with relapsed acute myeloid leukemia
url https://doi.org/10.1177/2324709617690747
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AT deepakravindranathanmd rhabdomyolysisfollowinginitiationofposaconazoleuseforantifungalprophylaxisinapatientwithrelapsedacutemyeloidleukemia
AT harpaulsgillmd rhabdomyolysisfollowinginitiationofposaconazoleuseforantifungalprophylaxisinapatientwithrelapsedacutemyeloidleukemia
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