A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis
Introduction: Previous studies have found ankylosis occurs as a part of the inflammatory process of aseptic root resorption initiated in a rat model.1 The physiologic mechanisms behind the development of dentoalveolar ankylosis and healing response are still unclear. While receptor activator of nucl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2014-11-01
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| Series: | Australasian Orthodontic Journal |
| Online Access: | https://doi.org/10.2478/aoj-2014-0011 |
| Summary: | Introduction: Previous studies have found ankylosis occurs as a part of the inflammatory process of aseptic root resorption initiated in a rat model.1 The physiologic mechanisms behind the development of dentoalveolar ankylosis and healing response are still unclear. While receptor activator of nuclear factor-κβ ligand (RANKL), receptor activator of nuclear factor-κβ (RANK) and osteoprotegerin (OPG) have gained momentum in the understanding of resorption, no study to date has investigated their role in dentoalveolar ankylosis. |
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| ISSN: | 2207-7480 |