A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis
Introduction: Previous studies have found ankylosis occurs as a part of the inflammatory process of aseptic root resorption initiated in a rat model.1 The physiologic mechanisms behind the development of dentoalveolar ankylosis and healing response are still unclear. While receptor activator of nucl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2014-11-01
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| Series: | Australasian Orthodontic Journal |
| Online Access: | https://doi.org/10.2478/aoj-2014-0011 |
| _version_ | 1797752427859935232 |
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| author | Curl Linda Tan Chien Wei Dreyer Craig W. Sampson Wayne |
| author_facet | Curl Linda Tan Chien Wei Dreyer Craig W. Sampson Wayne |
| author_sort | Curl Linda |
| collection | DOAJ |
| description | Introduction: Previous studies have found ankylosis occurs as a part of the inflammatory process of aseptic root resorption initiated in a rat model.1 The physiologic mechanisms behind the development of dentoalveolar ankylosis and healing response are still unclear. While receptor activator of nuclear factor-κβ ligand (RANKL), receptor activator of nuclear factor-κβ (RANK) and osteoprotegerin (OPG) have gained momentum in the understanding of resorption, no study to date has investigated their role in dentoalveolar ankylosis. |
| first_indexed | 2024-03-12T17:04:16Z |
| format | Article |
| id | doaj.art-ab5f34a46da249cc96b49929b5c1150e |
| institution | Directory Open Access Journal |
| issn | 2207-7480 |
| language | English |
| last_indexed | 2024-03-12T17:04:16Z |
| publishDate | 2014-11-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Australasian Orthodontic Journal |
| spelling | doaj.art-ab5f34a46da249cc96b49929b5c1150e2023-08-07T06:57:55ZengSciendoAustralasian Orthodontic Journal2207-74802014-11-0130214315110.2478/aoj-2014-0011A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosisCurl Linda0Tan Chien Wei1Dreyer Craig W.2Sampson Wayne31Orthodontic Unit, The School of Dentistry, The University of Adelaide, South Australia, Australia1Orthodontic Unit, The School of Dentistry, The University of Adelaide, South Australia, Australia1Orthodontic Unit, The School of Dentistry, The University of Adelaide, South Australia, Australia1Orthodontic Unit, The School of Dentistry, The University of Adelaide, South Australia, AustraliaIntroduction: Previous studies have found ankylosis occurs as a part of the inflammatory process of aseptic root resorption initiated in a rat model.1 The physiologic mechanisms behind the development of dentoalveolar ankylosis and healing response are still unclear. While receptor activator of nuclear factor-κβ ligand (RANKL), receptor activator of nuclear factor-κβ (RANK) and osteoprotegerin (OPG) have gained momentum in the understanding of resorption, no study to date has investigated their role in dentoalveolar ankylosis.https://doi.org/10.2478/aoj-2014-0011 |
| spellingShingle | Curl Linda Tan Chien Wei Dreyer Craig W. Sampson Wayne A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis Australasian Orthodontic Journal |
| title | A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis |
| title_full | A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis |
| title_fullStr | A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis |
| title_full_unstemmed | A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis |
| title_short | A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis |
| title_sort | qualitative investigation of rankl rank and opg in a rat model of transient ankylosis |
| url | https://doi.org/10.2478/aoj-2014-0011 |
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