Development of a theoretical framework for analyzing cerebrospinal fluid dynamics
<p>Abstract</p> <p>Background</p> <p>To date hydrocephalus researchers acknowledge the need for rigorous but utilitarian fluid mechanics understanding and methodologies in studying normal and hydrocephalic intracranial dynamics. Pressure volume models and electric circu...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-09-01
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| Series: | Cerebrospinal Fluid Research |
| Online Access: | http://www.cerebrospinalfluidresearch.com/content/6/1/12 |
| _version_ | 1818325882345881600 |
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| author | Vedel Søren Voorhees Abram Cohen Benjamin Wei Timothy |
| author_facet | Vedel Søren Voorhees Abram Cohen Benjamin Wei Timothy |
| author_sort | Vedel Søren |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>To date hydrocephalus researchers acknowledge the need for rigorous but utilitarian fluid mechanics understanding and methodologies in studying normal and hydrocephalic intracranial dynamics. Pressure volume models and electric circuit analogs introduced pressure into volume conservation; but control volume analysis enforces independent conditions on pressure and volume. Previously, utilization of clinical measurements has been limited to understanding of the relative amplitude and timing of flow, volume and pressure waveforms; qualitative approaches without a clear framework for meaningful quantitative comparison.</p> <p>Methods</p> <p>Control volume analysis is presented to introduce the reader to the theoretical background of this foundational fluid mechanics technique for application to general control volumes. This approach is able to directly incorporate the diverse measurements obtained by clinicians to better elucidate intracranial dynamics and progression to disorder.</p> <p>Results</p> <p>Several examples of meaningful intracranial control volumes and the particular measurement sets needed for the analysis are discussed.</p> <p>Conclusion</p> <p>Control volume analysis provides a framework to guide the type and location of measurements and also a way to interpret the resulting data within a fundamental fluid physics analysis.</p> |
| first_indexed | 2024-12-13T11:51:32Z |
| format | Article |
| id | doaj.art-ab60fb1ba4e942f18d7c6063e0446f67 |
| institution | Directory Open Access Journal |
| issn | 1743-8454 |
| language | English |
| last_indexed | 2024-12-13T11:51:32Z |
| publishDate | 2009-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Cerebrospinal Fluid Research |
| spelling | doaj.art-ab60fb1ba4e942f18d7c6063e0446f672022-12-21T23:47:20ZengBMCCerebrospinal Fluid Research1743-84542009-09-01611210.1186/1743-8454-6-12Development of a theoretical framework for analyzing cerebrospinal fluid dynamicsVedel SørenVoorhees AbramCohen BenjaminWei Timothy<p>Abstract</p> <p>Background</p> <p>To date hydrocephalus researchers acknowledge the need for rigorous but utilitarian fluid mechanics understanding and methodologies in studying normal and hydrocephalic intracranial dynamics. Pressure volume models and electric circuit analogs introduced pressure into volume conservation; but control volume analysis enforces independent conditions on pressure and volume. Previously, utilization of clinical measurements has been limited to understanding of the relative amplitude and timing of flow, volume and pressure waveforms; qualitative approaches without a clear framework for meaningful quantitative comparison.</p> <p>Methods</p> <p>Control volume analysis is presented to introduce the reader to the theoretical background of this foundational fluid mechanics technique for application to general control volumes. This approach is able to directly incorporate the diverse measurements obtained by clinicians to better elucidate intracranial dynamics and progression to disorder.</p> <p>Results</p> <p>Several examples of meaningful intracranial control volumes and the particular measurement sets needed for the analysis are discussed.</p> <p>Conclusion</p> <p>Control volume analysis provides a framework to guide the type and location of measurements and also a way to interpret the resulting data within a fundamental fluid physics analysis.</p>http://www.cerebrospinalfluidresearch.com/content/6/1/12 |
| spellingShingle | Vedel Søren Voorhees Abram Cohen Benjamin Wei Timothy Development of a theoretical framework for analyzing cerebrospinal fluid dynamics Cerebrospinal Fluid Research |
| title | Development of a theoretical framework for analyzing cerebrospinal fluid dynamics |
| title_full | Development of a theoretical framework for analyzing cerebrospinal fluid dynamics |
| title_fullStr | Development of a theoretical framework for analyzing cerebrospinal fluid dynamics |
| title_full_unstemmed | Development of a theoretical framework for analyzing cerebrospinal fluid dynamics |
| title_short | Development of a theoretical framework for analyzing cerebrospinal fluid dynamics |
| title_sort | development of a theoretical framework for analyzing cerebrospinal fluid dynamics |
| url | http://www.cerebrospinalfluidresearch.com/content/6/1/12 |
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