Integration of Within-Cell Experimental Data With Multi-Compartmental Modeling Predicts H-Channel Densities and Distributions in Hippocampal OLM Cells

Integration of Within-Cell Experimental Data With Multi-Compartmental Modeling Predicts H-Channel Densities and Distributions in Hippocampal OLM Cells

Determining biophysical details of spatially extended neurons is a challenge that needs to be overcome if we are to understand the dynamics of brain function from cellular perspectives. Moreover, we now know that we should not average across recordings from many cells of a given cell type to obtain...

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Bibliographic Details
Main Authors: Vladislav Sekulić, Feng Yi, Tavita Garrett, Alexandre Guet-McCreight, J. Josh Lawrence, Frances K. Skinner
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
hippocampus
interneuron
inhibitory cell
dendrite
h-channels
multi-compartment model
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00277/full

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