Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis
Pandoraea species are considered as emerging pathogens in people with cystic fibrosis (CF). The contribution of these organisms to disease progression in CF patients is not fully understood owing in large measure to the scant reports in clinical and research literature describing their colonisation...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-05-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00692/full |
| _version_ | 1818619101031956480 |
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| author | Mark eAmbrose Roslyn eMalley Roslyn eMalley Sanchia eWarren Sean Anthony Beggs Sean Anthony Beggs Oliver Frank Edmund Swallow Belinda eMcEwan David eStock Louise Frances Roddam |
| author_facet | Mark eAmbrose Roslyn eMalley Roslyn eMalley Sanchia eWarren Sean Anthony Beggs Sean Anthony Beggs Oliver Frank Edmund Swallow Belinda eMcEwan David eStock Louise Frances Roddam |
| author_sort | Mark eAmbrose |
| collection | DOAJ |
| description | Pandoraea species are considered as emerging pathogens in people with cystic fibrosis (CF). The contribution of these organisms to disease progression in CF patients is not fully understood owing in large measure to the scant reports in clinical and research literature describing their colonisation of CF patients and their associated virulence determinants. In an effort to increase awareness and evidence for Pandoraea spp. infection in people with CF, and to stimulate research aimed at unravelling the pathogenic properties of Pandoraea, we report a case of a 26-year-old Australian (Tasmanian) man with CF who was chronically infected with Pandoraea pnomenusa for at least one year prior to his death from respiratory failure. In addition, we describe for the first time evidence suggesting that this bacterium is a facultative anaerobe and report on the availability of a whole genome sequence for this organism. To the best of our knowledge, this report represents only the second clinical case study of P. pnomenusa infection in the world, and the first in an Australian CF patient. |
| first_indexed | 2024-12-16T17:32:07Z |
| format | Article |
| id | doaj.art-ab6727acdb0541a2881735ac61a69cd4 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-16T17:32:07Z |
| publishDate | 2016-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-ab6727acdb0541a2881735ac61a69cd42022-12-21T22:22:54ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2016-05-01710.3389/fmicb.2016.00692181641Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosisMark eAmbrose0Roslyn eMalley1Roslyn eMalley2Sanchia eWarren3Sean Anthony Beggs4Sean Anthony Beggs5Oliver Frank Edmund Swallow6Belinda eMcEwan7David eStock8Louise Frances Roddam9University of TasmaniaUniversity of TasmaniaRoyal Hobart HospitalRoyal Hobart HospitalUniversity of TasmaniaRoyal Hobart HospitalUniversity of TasmaniaRoyal Hobart HospitalRoyal Hobart HospitalUniversity of TasmaniaPandoraea species are considered as emerging pathogens in people with cystic fibrosis (CF). The contribution of these organisms to disease progression in CF patients is not fully understood owing in large measure to the scant reports in clinical and research literature describing their colonisation of CF patients and their associated virulence determinants. In an effort to increase awareness and evidence for Pandoraea spp. infection in people with CF, and to stimulate research aimed at unravelling the pathogenic properties of Pandoraea, we report a case of a 26-year-old Australian (Tasmanian) man with CF who was chronically infected with Pandoraea pnomenusa for at least one year prior to his death from respiratory failure. In addition, we describe for the first time evidence suggesting that this bacterium is a facultative anaerobe and report on the availability of a whole genome sequence for this organism. To the best of our knowledge, this report represents only the second clinical case study of P. pnomenusa infection in the world, and the first in an Australian CF patient.http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00692/fullCystic FibrosisInfectionLungAnaerobePandoraea |
| spellingShingle | Mark eAmbrose Roslyn eMalley Roslyn eMalley Sanchia eWarren Sean Anthony Beggs Sean Anthony Beggs Oliver Frank Edmund Swallow Belinda eMcEwan David eStock Louise Frances Roddam Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis Frontiers in Microbiology Cystic Fibrosis Infection Lung Anaerobe Pandoraea |
| title | Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis |
| title_full | Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis |
| title_fullStr | Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis |
| title_full_unstemmed | Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis |
| title_short | Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis |
| title_sort | pandoraea pnomenusa isolated from an australian patient with cystic fibrosis |
| topic | Cystic Fibrosis Infection Lung Anaerobe Pandoraea |
| url | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00692/full |
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